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UnknownModeling and simulation at the interface of nonclinical and early clinical drug development.
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S-EPMC3600756 | biostudies-literature
UnknownSystems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.
Not available
S-EPMC8384661 | biostudies-literature
UnknownCharacterizing QT interval prolongation in early clinical development: a case study with methadone.
Not available
S-EPMC5461648 | biostudies-literature
UnknownThe impact of composite AUC estimates on the prediction of systemic exposure in toxicology experiments.
Not available
S-EPMC4432106 | biostudies-literature
UnknownPharmacokinetic-pharmacodynamic modelling of drug-induced QTc interval prolongation in man: prediction from in vitro human ether-a-go-go-related gene binding and functional inhibition assays and conscious dog studies.
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S-EPMC5055135 | biostudies-literature
UnknownModel-based prediction of the acute and long-term safety profile of naproxen in rats.
Not available
S-EPMC4523341 | biostudies-literature
UnknownDisease Systems Analysis of Bone Mineral Density and Bone Turnover Markers in Response to Alendronate, Placebo, and Washout in Postmenopausal Women.
Not available
S-EPMC5193000 | biostudies-literature
UnknownIntegration of PKPD relationships into benefit-risk analysis.
Not available
S-EPMC4631171 | biostudies-literature
UnknownCurrent Limitations and Perspectives of Chimeric Antigen Receptor-T-Cells in Acute Myeloid Leukemia.
Not available
S-EPMC8699597 | biostudies-literature
UnknownToxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies.
Not available
S-EPMC7793717 | biostudies-literature
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