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ProteomicsDAPK3 modulates migration and invasion of triple negative breast cancers
A mass spectrometry (MS)-based kinase inhibitor pulldown assay (KIPA) was applied to analyze 16 patient-derived xenografts (PDXs) leading to the discovery that Death-Associated Protein Kinase 3 (DAPK3) is significantly and specifically overexpressed in triple negative breast cancer (TNBC). Validatio...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049187 | Pride
Luzp1 Emt Breast cancer Cancer Dapk3 Pdx 
GenomicsRNA-Seq analysis of SUM159 DAPK3 knockout (KO) cells and control cells
RNA-Seq analysis of SUM159 DAPK3 knockout (KO) cells and control cells
PRJNA1140237 | ENA
TranscriptomicsRNA-Seq analysis of SUM159 DAPK3 knockout (KO) cells and control cells
We conducted RNA sequencing of SUM159 DAPK3 KO and control cells followed by Gene Set Enrichment Analysis (GSEA) to identify altered gene expression pathways by DAPK3 knockout. Epithelial-mesenchymal transition (EMT) pathway was the top significantly down-regulated pathway in SUM159 DAPK3 KO cells a...
ORGANISM(S): Homo sapiens 
2024-10-10 | GSE273142 | GEO
UnknownTargeting Pim Kinases and DAPK3 to Control Hypertension.
Not available
S-EPMC6863095 | biostudies-literature
UnknownDAPK3 suppresses acini morphogenesis and is required for mouse development.
Not available
S-EPMC4336824 | biostudies-literature
UnknownDAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy.
Not available
S-EPMC7937684 | biostudies-literature
Methylation profilingInsulin and glucose alter death-associated protein kinase 3 (DAPK3) DNA methylation in human skeletal muscle
DNA methylation marks are altered by environmental factors. We tested the hypothesis that DNA methylation is altered in skeletal muscle in response to either insulin or glucose exposure. We performed a genome-wide DNA methylation analysis in skeletal muscle from healthy men before and after insulin ...
ORGANISM(S): Homo sapiens 
2017-01-01 | GSE87655 | GEO
UnknownThe tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway.
Not available
S-EPMC8300883 | biostudies-literature
UnknownClassical swine fever virus NS5A protein activates autophagy via the PP2A-DAPK3-Beclin 1 axis.
Not available
S-EPMC10734420 | biostudies-literature
UnknownYTHDF2 promotes gallbladder cancer progression and gemcitabine resistance via m6A-dependent DAPK3 degradation.
Not available
S-EPMC10637062 | biostudies-literature
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