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TranscriptomicsResponse of C2C12-hN1∆ECD to DAPT washout
C2C12 cells expressing constitutively active hN1∆ECD were activated by complete DAPT washout for 1h or 6h, or left in 10 uM DAPT 2 Samples and 1 Control
ORGANISM(S): Mus musculus 
2016-09-04 | E-GEOD-72847 | biostudies-arrayexpress
ProteomicsIdentification of naturally short gamma-secretase substrates
The intramembrane protease gamma-secretase has broad physiological functions, but also contributes to Notch-dependent tumors and Alzheimer’s disease. To identify naturally short substrates and non-substrates of gamma-secretase, we used four human cell lines of different tissue origins, breast cancer...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD045701 | Pride
Dapt Human Gamma-secretase Intramembrane protease 
TranscriptomicsGenome-wide analysis of gene expression changes in mouse keratinocytes induced by treatment with DAPT
Analysis of gene expression changes that occur in keratinocytes during reprogramming when they are treated with DAPT, a small molecule gamma-secretase inhibitor. The hypothesis tested in the present study was that Notch inhibition by DAPT treatment would promote reprogramming by inhibiting p21 activ...
ORGANISM(S): Mus musculus 
2014-05-25 | E-GEOD-35090 | biostudies-arrayexpress
GenomicsDAPT-dependent regulation of zebrafish Muller glial cell chromatin accessibility
DAPT-dependent regulation of zebrafish Muller glial cell chromatin accessibility
PRJNA671686 | ENA
GenomicsDAPT-dependent regulation of zebrafish Muller glial cell gene expression
DAPT-dependent regulation of zebrafish Muller glial cell gene expression
PRJNA671696 | ENA
TranscriptomicsRNA-seq on Hu5/KD3 cells cultured with or without DAPT at proliferating stage
DAPT(a Notch inhibitor) promted myotube formation of human muscle progenitors. To clarify the Notch signal-responsive genes that inhibit or augment myotube formation, we examined the gene expression in Hu5/KD3 (immortalized human myoblast) treated with DAPT for three days by RNA-seq analysis. Hu5/KD...
ORGANISM(S): Homo sapiens 
2020-03-07 | E-MTAB-8825 | biostudies-arrayexpress
UnknownMyocardial Infarction Risk After Discontinuation of Thienopyridine Therapy in the Randomized DAPT Study (Dual Antiplatelet Therapy).
Not available
S-EPMC5469374 | biostudies-literature
TranscriptomicsResponse of C2C12-hN1∆ECD to DAPT washout
C2C12 cells expressing constitutively active hN1∆ECD were activated by complete DAPT washout for 1h or 6h, or left in 10 uM DAPT
ORGANISM(S): Mus musculus 
2016-09-04 | GSE72847 | GEO
UnknownShort versus prolonged dual antiplatelet therapy (DAPT) duration after coronary stent implantation: A comparison between the DAPT study and 9 other trials evaluating DAPT duration.
Not available
S-EPMC5607128 | biostudies-literature
UnknownEstimation of DAPT Study Treatment Effects in Contemporary Clinical Practice: Findings From the EXTEND-DAPT Study.
Not available
S-EPMC8748407 | biostudies-literature
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