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MetabolomicsMetabolomic Responses of Arabidopsis Suspension Cells to Bicarbonate under Light and Dark Conditions
Global CO2 level presently recorded at 400 ppm is expected to reach 550 ppm in 2050, an increment likely to impact plant growth and productivity. Using targeted LC-MS and GC-MS platforms we quantified 229 and 29 metabolites, respectively in a time-course study to reveal short-term responses to diffe...
2017-04-25 | MTBLS311 | MetaboLights
MetabolomicsA neurotoxic cellular stress response linked to dark microglia and toxic lipid secretion

Microglia, the brain’s primary resident immune cells, can assume various phenotypes with diverse functional outcomes on brain homeostasis. In Alzheimer’s disease (AD), where microglia are a leading causal cell type, the identity of microglia subsets that drive neurodegeneration remains unresolved...

2024-12-20 | MTBLS11942 | MetaboLights
MetabolomicsThe synergistic growth promoting mechanism of ""internal and external"" microbiota for maize growth mediated by dark septate endophytes

BACKGROUND: The coevolution and interaction between plants and microorganisms have long been a subject of significant research interest. Dark septate endophytes (DSE) have garnered great attention in contemporary research due to their functional diversity, in vitro cultivation ab...

2023-12-15 | MTBLS8903 | MetaboLights
MetabolomicsDetermination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets
Spatial metabolomics using mass spectrometry imaging (MSI) is a powerful tool to map hundreds to thousands of metabolites in biological systems. One major challenge in MSI is the annotation of m/z values, which is substantially complicated by background ions introduced throughout the c...
2021-06-15 | MTBLS954 | MetaboLights
MetabolomicsIlluminating the dark space of neutral glycosphingolipidome by selective enrichment and profiling at multi-structural levels

Glycosphingolipids (GSLs) are essential components of cell membranes, particularly enriched in the nervous system. Altered molecular distributions of GSLs are increasingly associated with human diseases, emphasizing the significance of lipidomic profiling. Traditional GSL analysis methods are ham...

2024-06-25 | MTBLS10400 | MetaboLights
TranscriptomicsTranscriptional responses to dark induced senescence in Nicotiana tabacum.
Gene expression was measured in leaves from dark treated tobacco plants to investigate the changes associated with dark induced senescence.
ORGANISM(S): Nicotiana tabacum 
2011-05-01 | E-MTAB-602 | biostudies-arrayexpress
TranscriptomicsGenome wide rhythmic transcription under light/dark cycles in Ostreococcus tauri
Genome wide rhythmic transcription under light/dark cycles is associated with sequential transcription of specific biological processes genes in Ostreococcus tauri. Transcriptional profiling of Ostreococcus tauri under light/dark cycles. In order to identify genes with a diurnal rhythm, cells entrai...
ORGANISM(S): Ostreococcus tauri 
2010-04-20 | E-GEOD-16422 | biostudies-arrayexpress
ProteomicsSyn6803 Pyk-ox under light and dark
Effect of pyruvate kinase (Sll0587) overexpression under both light and dark conditions.
ORGANISM(S): Cellular Organisms 
2024-10-16 | PXD053484 | JPOST Repository
TranscriptomicsArabidopsis De-etiolated 1 Represses Photomorphogenesis by Positively Regulating Phytochrome Interacting Factors in the Dark
Arabidopsis seedlings undergo photomorphogenic development even in darkness when the function of De-etiolated 1 (DET1), a repressor of photomorphogenesis, is disrupted. Our results indicate that DET1 directly interacts with a group of transcription factors known as the phytochrome-interacting factor...
ORGANISM(S): Arabidopsis thaliana 
2015-03-19 | E-GEOD-60835 | biostudies-arrayexpress
TranscriptomicsGene regulation of carbon fixation, storage and utilization in the diatom Phaeodactylum tricornutum acclimated to light/dark cycles
Regulation of carbon metabolism in the diatom Phaeodactylum tricornutum at cell, metabolite and gene expression level in exponential fed-batch cultures is reported. Transcriptional profiles and cell chemistry sampled simultaneously at all time-points provide a comprehensive data set on carbon incorp...
ORGANISM(S): Phaeodactylum tricornutum 
2013-03-01 | E-GEOD-42514 | biostudies-arrayexpress
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