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TranscriptomicsTranscriptome profiling in Engrailed2 knockout mice reveals common molecular pathways associated with ASD.
Background: Transcriptome analysis has been used in autism spectrum disorder (ASD) to unravel common pathogenic pathways based on the assumption that distinct rare genetic variants or epigenetic modifications affect common biological pathways dysregulated in ASD. To unravel recurrent ASD-related neu...
ORGANISM(S): Mus musculus 
2013-12-23 | E-GEOD-51612 | biostudies-arrayexpress
ProteomicsPolysomal profiling coupled to allele-specific proteomics reveals an EIF4H tranSNP allele possessing higher mRNA translation potential
To search for genetic sources of allele-specific mRNA translation, we leveraged heterozygous polymorphisms and variants present in the exome of HCT116-derived cell lines, computing allelic fractions in total and polysome-associated RNA from RNA-seq data. Allelic imbalance in polysomal RNA led us to ...
ORGANISM(S): Homo Sapiens 
PXD073180 | panorama
UnknownSterile inflammation via TRPM8 RNA-dependent TLR3-NF-B/IRF3 activation promotes antitumor immunity in prostate cancer
Not available
S-SCDT-10_1038-S44318-024-00040-5 | biostudies-other
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