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MetabolomicsLACTIN-V (Lactobacillus crispatus CTV-05) leads to microbial and immune modulation in pregnant women at risk of spontaneous preterm birth: FLIP-1 study

Preterm birth (PTB) remains a leading cause of neonatal morbidity and mortality, with no new preventive therapeutics introduced since the 1970s. Evidence increasingly implicates adverse vaginal microbiome-immune interactions in its aetiology. We report the effects of the live biotherapeutic, Lact...

2026-10-02 | MTBLS15899 | MetaboLights
GenomicsThe In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J gene segments, has not previously been characterized in vivo. Here we demonstrate that RAG protein binding occurs in a highly focal manner to a small reg...
ORGANISM(S): Mus musculus 
2010-04-19 | E-GEOD-21207 | biostudies-arrayexpress
TranscriptomicsHypothalamic transcriptome plasticity in two rodent species reveals divergent differential gene expression but conserved pathways
We have addressed the question of how different rodent species cope with the life-threatening homeostatic challenge of dehydration at the level of transcriptome modulation in the supraoptic nucleus (SON), a specialised hypothalamic neurosecretory apparatus responsible for the production of the antid...
ORGANISM(S): Mus musculus 
2010-11-29 | E-GEOD-25574 | biostudies-arrayexpress
GenomicsEarly isolated v-lesion may not truly represent a rejection of kidney allograft
Early isolated v-lesion may not truly represent a rejection of kidney allograft
PRJNA472352 | ENA
Proteomics2019 Brecht et al. RAG1 vAbl BioID LC-MS/MS
To identify mechanisms that regulate V(D)J recombination, we used proximity-dependent biotin identification to analyze the interactomes of full length and truncated forms of RAG1 in pre-B cells. This revealed an association of RAG1 with numerous nucleolar proteins in a manner dependent on amino acid...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-02 | PXD016221 | Pride
Pre b cell Vabl cell V(d)j recombination Bioid Rag1 
GenomicsChIP-seq analysis of genome-wide DNA binding by transcription factors HapR and LuxO in Vibrio cholerae
The experiment contains ChIP-seq data for Vibrio cholerae strain E7946. The strain was grown at 37 degrees in LB medium and crosslinked with 1 % (v/v) formaldehyde. After sonication, to break open cells and fragment DNA, immunoprecipitations were done using anti-FLAG antibodies. Libraries were prepa...
ORGANISM(S): Vibrio cholerae 
2023-03-29 | E-MTAB-11906 | biostudies-arrayexpress
UnknownType V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.
Not available
S-EPMC7415659 | biostudies-literature
UnknownPhylogeny-Informed Synthetic Biology Reveals Unprecedented Structural Novelty in Type V Glycopeptide Antibiotics.
Not available
S-EPMC9136965 | biostudies-literature
UnknownHelium-induced defect clustering and thermal evolution in V-4Cr-4Ti: an alloy for fusion reactor applications.
Not available
S-EPMC12603076 | biostudies-literature
UnknownSwitch II mutants reveal coupling between the nucleotide- and actin-binding regions in myosin V.
Not available
S-EPMC3368122 | biostudies-literature
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