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no omics definedTranscription profiling of lung from mice with doxycycline-induced TGFa-over-expression for 6 up to weeks, and up to 6 weeks of recovery to study TGFa-induced pulmonary fibrosis
Time series response to Doxycycline-induced TGFa-overexpression for 6 up to weeks, and up to 6 weeks of recovery.
ORGANISM(S): Mus musculus 
2007-05-23 | E-MEXP-966 | biostudies-arrayexpress
TranscriptomicsEffect of AZA on gene expression of multiple breast, colon, and ovarian cell lines [expression]
Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidin...
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-57341 | biostudies-arrayexpress
TranscriptomicsImmune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers [methylation]
Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidin...
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-57342 | biostudies-arrayexpress
TranscriptomicsInhibition of MEK and PI3K alone or in combination alters the transcriptome of the lung during TGF?-induced pulmonary fibrosis
Pulmonary fibrosis is often triggered by an epithelial injury resulting in the formation of fibrotic lesions in the lung, which progress to impair gas exchange and ultimately cause death. Recent clinical trials using drugs that target either inflammation or a specific molecule have failed, suggestin...
ORGANISM(S): Mus musculus 
2013-12-03 | E-GEOD-52854 | biostudies-arrayexpress
UnknownEvaluation of appendicitis risk prediction models in adults with suspected appendicitis.
Not available
S-EPMC6972511 | biostudies-literature
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