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TFIID is a general transcription factor required for transcription of most protein-coding genes by RNA polymerase II. TAF7L is an X-linked germ cell-specific paralogue of TAF7, which is a generally expressed component of TFIID. Here we report the generation of Taf7l mutant mice by homologous recombi...
ORGANISM(S): Mus musculus 
35 paired samples from initial diagnosis and first marrow relapse. Genes and pathways differentiating diagnosis and relapse were identified. Potential therapeutic targets were also identified. Experiment Overall Design: 35 patients with samples from initial diagnosis and first marrow relapse.
ORGANISM(S): Homo sapiens 
This SuperSeries comprises the following subset Series:; GSE3910: 35 patients at diagnosis and relapse; GSE3911: 60 samples obtained at relapse Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
Gene expression profiles were analyzed from 60 children with first bone marrow relapse. Genes and pathways differentiating early vs. late relapse were identified. Signatures predicting early response to therapy were also identified. Experiment Overall Design: 60 patients at relapse were analyzed
ORGANISM(S): Homo sapiens 
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonel...
ORGANISM(S): Bos taurus 
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