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MetabolomicsA Combined Metabolomic and Proteomic Investigation of the Effects of a Failure to Express Dystrophin in the Mouse Heart
Muscle degeneration in the heart of 1-9 month-old mdx mice (a model for Duchenne muscular dystrophy) has been monitored using metabolomic and proteomic approaches. In both data sets, a pronounced aging trend was detected in control and mdx mice, and this trend was separate from the disease process. ...
2017-03-14 | MTBLS256 | MetaboLights
MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
MetabolomicsExamination of human osteoarchaeological remains as a feasible source of polar and apolar metabolites to study past conditions
Metabolomics is a modern tool that aids in our understanding of the molecular changes in organisms. Archaeological science is a branch of archaeology that explores different archaeological materials using modern analytical tools. Human osteoarchaeological material are a frequent finding in archaeolo...
2022-07-04 | MTBLS4437 | MetaboLights
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine, plasma and liver NMR assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non-relevant doses or in combination with other r...
2018-05-01 | MTBLS602 | MetaboLights
MetabolomicsMetabolite profiling of tubers of an early- and a late-maturing potato line and their grafts

INTRODUCTION: Earliness of tuberisation and the quality of potato tubers are important traits in potato breeding. The qualitative traits rely on the metabolite profile of tubers, which are storage organs and net importers of assimilates. Thus, the quality of tubers largely depend...

2023-09-12 | MTBLS4445 | MetaboLights
UnknownMolecular Dynamics of the Davies Ambimodal C-H Functionalization/Cope Rearrangement Reaction.
Not available
S-EPMC12442840 | biostudies-literature
UnknownThe isolation and characterization of a new snake venom cysteine-rich secretory protein (svCRiSP) from the venom of the Southern Pacific rattlesnake and its effect on vascular permeability.
Not available
S-EPMC6556137 | biostudies-literature
ProteomicsHypoxia promotes the generation of a versican-rich extracellular matrix by human coronary artery endothelial cells
• Exposure of endothelial cells (HCAECs) to hypoxia alters gene an protein expression • Genes and proteins related to endothelial dysfunction and activation are overexpressed • Hypoxia induces a versican-rich matrix with an altered glycosaminoglycan profile • This modified matrix perturbs cell adhes...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD052078 | Pride
Ecm Hypoxia Proteomics 
UnknownEdward Beresford Davies
Not available
S-EPMC1122466 | biostudies-literature
UnknownLiraglutide and cardiovascular outcomes in adults with overweight or obesity: A post hoc analysis from SCALE randomized controlled trials.
Not available
S-EPMC5836948 | biostudies-literature
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