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ProteomicsGeneration of aggregates of alpha-lactalbumin by UV-B light exposure
Whey proteins are widely used as ingredients in the form of aggregates to obtain certain functionalities in food applications. The aim of this study was to understand how UV illumination generates aggregates of alpha-lactalbumin (a-LA) as an alternative to heat treatments traditionally used for indu...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2019-12-16 | MSV000084695 | MassIVE
ProteomicsLabel-free mass spectrometry analysis of laminin with induced oxidations and chlorination’s facilitated with hypochlorous acid and myeloperoxidase treatments.
Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation, via the enz...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-05 | PXD022056 | Pride
Ecm Lc-ms/ms Oxidation Extracellular matrix proteins Inflammation. Chlorination Laminin 
ProteomicsOXIPEP: mass spectrometry strategy to characterize protein carbonylation.
Here we describe a peptide-centric approach (OXIPEP), where carbonylated residues within proteins are derivatized with biotin-hydrazide, enriched and identified by mass spectrometry. The strength of the method lies in an improved protocol for elution of biotinylated peptides from monomeric avidin r...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2018-10-18 | PXD002966 | Pride
Protein carbonylation Bovine serum albumine Human plasma Biotin-hydrazide 
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