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UnknownR-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania.
Not available
S-EPMC11807225 | biostudies-literature
MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
UnknownPF-431396 hydrate inhibition of kinase phosphorylation during adherent-invasive Escherichia coli infection inhibits intra-macrophage replication and inflammatory cytokine release.
Not available
S-EPMC10333790 | biostudies-literature
UnknownGenome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome.
Not available
S-EPMC6294496 | biostudies-literature
UnknownOleacein and Foam Cell Formation in Human Monocyte-Derived Macrophages: A Potential Strategy Against Early and Advanced Atherosclerotic Lesions.
Not available
S-EPMC7243116 | biostudies-literature
UnknownTrypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic variation.
Not available
S-EPMC6753483 | biostudies-literature
UnknownInflammation associated ethanolamine facilitates infection by Crohn's disease-linked adherent-invasive Escherichia coli.
Not available
S-EPMC6557746 | biostudies-literature
UnknownMapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis.
Not available
S-EPMC9047441 | biostudies-literature
MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
UnknownComparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity.
Not available
S-EPMC5376240 | biostudies-literature
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