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TranscriptomicsComparison of post-mortem tissue from brain BA10 region between schizophrenic and control patients.
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Schizophrenia is a severe psychiatric disorder with a world-wide prevalence of 1%. The pathophysiology of the illness is not understood, but is thought to have a strong...
ORGANISM(S): Homo sapiens 
2009-08-13 | E-GEOD-17612 | biostudies-arrayexpress
UnknownEffects of canagliflozin, a sodium glucose co-transporter 2 inhibitor, on blood pressure and markers of arterial stiffness in patients with type 2 diabetes mellitus: a post hoc analysis.
Not available
S-EPMC5327537 | biostudies-literature
UnknownEfficacy and safety of canagliflozin in patients with type 2 diabetes based on history of cardiovascular disease or cardiovascular risk factors: a post hoc analysis of pooled data.
Not available
S-EPMC5361783 | biostudies-literature
ProteomicsIsolation and characterization of multi-protein complexes enriched in the K-Cl co-transporter 2 from brain plasma membranes
Kcc2 plays a critical role in determining the efficacy of synaptic inhibition, however, the cellular mechanism neurons use to regulate its membrane trafficking, stability and activity are ill-defined. To address these issues, we used affinity purification to isolate stable multi-protein complexes of...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-22 | PXD021368 | Pride
Kcc2 Phosphorylation Proteome Interactome 
UnknownSafety and tolerability of sitagliptin in clinical studies: a pooled analysis of data from 10,246 patients with type 2 diabetes.
Not available
S-EPMC3161395 | biostudies-literature
Genomicsena-DATASET-MDACC-02-02-2018-10:54:47:473-560 - samples
The oral and gut microbiomes of melanoma patients were characterized before the initiation of ant-PD1 immunotherapy, and compared to treatment response. Validation studies were performed in germ-free mice using stool from patients who responded/did not respond to ant-PD1 immunotherapy. All baseline...
EGAD00001003943 | EGA
UnknownA phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma.
Not available
S-EPMC5672925 | biostudies-literature
UnknownCan mental health treatments help prevent or reduce intimate partner violence in low- and middle-income countries? A systematic review.
Not available
S-EPMC6376658 | biostudies-literature
UnknownInfluence of cardiometabolic medications on abdominal aortic aneurysm growth in the UK Aneurysm Growth Study: metformin and angiotensin-converting enzyme inhibitors associated with slower aneurysm growth.
Not available
S-EPMC10763526 | biostudies-literature
TranscriptomicsComparison of post-mortem tissue from Brodman Brain BA22 region between schizophrenic and control patients
Transcriptional analysis of the superior temporal cortex (BA22) in schizophrenia: Pathway insight into disease pathology and drug development Schizophrenia is a highly debilitating psychiatric disorder which is known to have heritable genetic and environmental components. To gain some insight into t...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-21935 | biostudies-arrayexpress
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