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MetabolomicsTwo UGT84A Family Glycosyltransferases Regulate Phenol, Flavonoid, and Tannin Metabolism in Juglans regia (English Walnut)
We showed previously that gallic acid is produced in walnut from 3-dehydroshikimate by a shikimate dehydrogenase (JrSkDH). This study focuses on the next step in the hydrolysable tannin pathway, the formation of 1-O-galloyl-β-D-glucose from the phenolic gallic acid and UDP glucose by a glycos...
2022-10-11 | MTBLS2042 | MetaboLights
GenomicsA genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function (DNase-hypersensitivity)
Distal cell-type-specific regulatory elements may be located at very large distances from the genes that they control and are often hidden within intergenic regions or in introns of other genes. The development of methods that enable mapping of regions of open chromatin genome wide has greatly advan...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-52179 | biostudies-arrayexpress
TranscriptomicsA genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function (array)
Distal cell-type-specific regulatory elements may be located at very large distances from the genes that they control and are often hidden within intergenic regions or in introns of other genes. The development of methods that enable mapping of regions of open chromatin genome wide has greatly advan...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-52180 | biostudies-arrayexpress
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
UnknownIRAK-M Regulates Monocyte Trafficking to the Lungs in Response to Bleomycin Challenge.
Not available
S-EPMC7356730 | biostudies-literature
UnknownPeronosporaceae species causing downy mildew diseases of Poaceae, including nomenclature revisions and diagnostic resources.
Not available
S-EPMC9355112 | biostudies-literature
UnknownClinafloxacin for Treatment of Burkholderia cenocepacia Infection in a Cystic Fibrosis Patient.
Not available
S-EPMC4704148 | biostudies-literature
UnknownDeploying dengue-suppressing Wolbachia : Robust models predict slow but effective spatial spread in Aedes aegypti.
Not available
S-EPMC5476474 | biostudies-literature
UnknownLongitudinal associations between diurnal cortisol variation and later-life cognitive impairment.
Not available
S-EPMC6988984 | biostudies-literature
TranscriptomicsshRNA profiling of human Ewings sarcoma samples to produce a molecular function map of Ewinga??s Sarcoma
EWS-FLI1 is a chimeric ETS transcription factor that is, due to a chromosomal rearrangement, specifically expressed in Ewing’s sarcoma family tumors (ESFT) and is thought to be the initiating event in the development of the disease. Previous genomic profiling experiments have identified a number o...
ORGANISM(S): Homo sapiens 
2009-05-11 | E-GEOD-14543 | biostudies-arrayexpress
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