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UnknownImpact of Prognostic Discussions on the Patient-Physician Relationship: Prospective Cohort Study.
Not available
S-EPMC5773842 | biostudies-literature
UnknownClinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.
Not available
S-EPMC6366813 | biostudies-literature
ProteomicsMass spectrometry proteomics reveals proteins that function in mTOR regulated selective autophagy
We used proteomic profiling to identify proteins in the mTOR-autophagy axis. Mouse cell lines lacking individual autophagy genes (Atg5 or Ulk1/Ulk2) were treated with an mTOR inhibitor to induce autophagy and cultured in media with either glucose or galactose. Mass spectrometry proteome profiling re...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-23 | PXD014990 | Pride
Selective autophagy  mtor  mass spectrometry proteomics  calcoco1  lc3  er-phagy  atg5  ulk1  ulk2 
TranscriptomicsA methyl-deviator epigenotype of estrogen-receptor-positive breast carcinoma is associated with malignant biology
We broadly profiled DNA methylation in breast cancers (n=351) and benign parenchyma (n=47) for correspondence with disease phenotype using formalin-fixed paraffin-embedded (FFPE) diagnostic surgical pathology specimens. Exploratory analysis revealed a distinctive primary invasive carcinoma subclass ...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-29428 | biostudies-arrayexpress
ModelsCD4 T cell signaling
Caveolin-1 (CAV1) is a vital scaffold protein heterogeneously expressed in both healthy and malignant tissue. We focus on the role of CAV1 when overexpressed in T-cell leukemia. Previously, we have shown that CAV1 is involved in cell-to-cell communication, cellular proliferation, and immune synapse ...
3521 | Cell Collective
UnknownNiraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial.
Not available
S-EPMC9361481 | biostudies-literature
UnknownMeasuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016.
Not available
S-EPMC5986687 | biostudies-literature
UnknownSubnational mapping of HIV incidence and mortality among individuals aged 15-49 years in sub-Saharan Africa, 2000-18: a modelling study.
Not available
S-EPMC8187986 | biostudies-literature
UnknownGlobal, regional, and national burden of suicide, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
Not available
S-EPMC11876099 | biostudies-literature
UnknownGlobal burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
Not available
S-EPMC11120204 | biostudies-literature
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