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TranscriptomicsTranscription in Pronuclei and One- to Four-Cell Embryos Drives Early Development in a Nematode
A long-standing view of development is that transcription is silenced in the oocyte until early divisions in the embryo. The point at which major transcription is reactivated varies in different organisms, but is usually after the 2-cell stage. However, this model may not be universal. We used RNA-s...
ORGANISM(S): Ascaris suum 
2014-01-02 | E-GEOD-46277 | biostudies-arrayexpress
GenomicsWTCCC2 Reading and Mathematics (RM) samples
A WTCCC2 project genome-wide association study for reading and mathematics ability in 3665 12-year-old individuals from the UK, genotyped on the Affymetrix 6.0 array. Details of the WTCCC2 analysis can be found in Davis et al. [Nat. Commun. 2014 July;5:4204]
EGAS00001000886 | EGA
TranscriptomicsTranscriptome analysis of post-hatch breast muscle in legacy and modern broiler chickens reveals enrichment of several regulators of myogenic growth
We report the results of comparative transcriptional profiling in the pectoralis major muscle of a modern production broiler line (Ross 708) and a legacy broiler line inbred since the late 1940s (Illinois) focusing on metabolic differences and differences in myogenic growth regulators Differential g...
ORGANISM(S): Gallus gallus 
2015-03-31 | E-GEOD-65217 | biostudies-arrayexpress
TranscriptomicsGenistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner
To obtain an integrated view of gene regulation in response to environmental and endogenous estrogens on a genome-wide scale, we performed ChIP-seq, to identify estrogen receptor 1 (ER) binding sites, and RNA-seq in endometrial cancer cells exposed to bisphenol A (BPA; found in plastics), genistein ...
ORGANISM(S): Homo sapiens 
2012-06-13 | E-GEOD-38234 | biostudies-arrayexpress
TranscriptomicsCopper exposures on the endangered delta smelt
The delta smelt (Hypomesus transpacificus) is an endangered pelagic fish species endemic to the Sacramento-San Joaquin estuary, California, and considered an indicator of ecosystem health. The experimental combination of molecular biomarkers with higher level condition indicators may allow for inter...
ORGANISM(S): Hypomesus transpacificus 
2010-08-18 | E-GEOD-23238 | biostudies-arrayexpress
UnknownHelicobacter pylori serology is associated with worse overall survival in patients with melanoma treated with immune checkpoint inhibitors.
Not available
S-EPMC9272833 | biostudies-literature
TranscriptomicsRNA sequencing of human pancreatic cancer cell lines
RNA-seq profiling was conducted on human pancreatic cancer cell lines We measured the transcriptome in 14 human pancreatic cancer cell linees
ORGANISM(S): Homo sapiens 
2016-06-11 | E-GEOD-79669 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of human pancreatic adenocarcinoma cancer tissues
RNA-seq profiling was conducted on clinically-annotated human pancreatic adenocarcinoma cancer tissues We measured the transcriptome in 51 clinically-annotated human pancreatic adenocarcinoma cancer tissues
ORGANISM(S): Homo sapiens 
2016-06-11 | E-GEOD-79668 | biostudies-arrayexpress
GenomicsWTCCC2_RM - samples
WTCCC2 Reading and Mathematics ability (RM) samples from UK using the Affymetrix 6.0 array
EGAD00010000602 | EGA
UnknownPrediction and Classification of Alzheimer's Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers.
Not available
S-EPMC6805777 | biostudies-literature
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