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TranscriptomicsImprinted expression of genes and small RNA is triggered by localized demethylation of the maternal genome in rice endosperm
We report that rice endosperm shows a specific hypomethylation of DNA in the maternal genome, preferring regions of high DNA accessibility. Maternally expressed imprinted genes are enriched for hypomethylation at putative promoter regions and transcriptional termini, and paternally expressed genes a...
ORGANISM(S): Oryza sativa 
2013-05-01 | E-GEOD-44898 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of the human dorsal striatum in bipolar disorder
Bipolar disorder (BD) is a highly heritable and heterogeneous mental illness whose manifestations often include impulsive and risk-taking behavior. This particular phenotype suggests that abnormal striatal function could be involved in BD etiology, yet most transcriptomic studies of this disorder ha...
ORGANISM(S): Homo sapiens 
2016-08-10 | E-GEOD-80336 | biostudies-arrayexpress
UnknownImpact of Prognostic Discussions on the Patient-Physician Relationship: Prospective Cohort Study.
Not available
S-EPMC5773842 | biostudies-literature
TranscriptomicsFast and chronic ethanol tolerance - time course
To better understand the molecular mechanisms underlying ethanol action we have developed an assay system to study sensitivity and fast and chronic tolerance to the sedative effects of ethanol. Flies developed fast ethanol tolerance after single exposure to 50% of ethanol vapor for 40 min. Flies ca...
ORGANISM(S): Drosophila melanogaster 
2006-03-24 | E-GEOD-4531 | biostudies-arrayexpress
UnknownProtein-protein interactions of tandem affinity purified protein kinases from rice.
Not available
S-EPMC2723914 | biostudies-literature
UnknownAssociation of Metformin With the Development of Age-Related Macular Degeneration.
Not available
S-EPMC9936345 | biostudies-literature
UnknownEffect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial.
Not available
S-EPMC4123233 | biostudies-literature
UnknownMulti-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.
Not available
S-EPMC12273372 | biostudies-literature
UnknownWhole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Not available
S-EPMC4755714 | biostudies-literature
UnknownEfficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial.
Not available
S-EPMC8669605 | biostudies-literature
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