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UnknownRisk of major adverse cardiovascular events and all-cause mortality under treatment with GLP-1 RAs or the dual GIP/GLP-1 receptor agonist tirzepatide in overweight or obese adults without diabetes: a systematic review and meta-analysis.
Not available
S-EPMC11437580 | biostudies-literature
UnknownPhase III Intergroup Trial of Adjuvant Androgen Deprivation With or Without Mitoxantrone Plus Prednisone in Patients With High-Risk Prostate Cancer After Radical Prostatectomy: SWOG S9921.
Not available
S-EPMC5959197 | biostudies-literature
TranscriptomicsIGR_MITF_STUDY_BBRB
A recent study of the characteristics of coexisting melanoma and renal cell carcinoma RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia associated transcription factor (MITF) was proposed to act as a melanoma oncogene;...
ORGANISM(S): Homo sapiens 
2011-09-03 | E-TABM-1198 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of blood cells from hypertriglyceridemic men treated with docosahexaenoic acid shows suppression of LDLR and OLR1 gene expression.
Previously published results from our double-blind, placebo-controlled parallel study with docosahexaenoic acid (DHA) supplementation (3 g/d, 90 d) to hypertriglyceridemic men (39-66yr) showed that DHA reduced several risk factors for cardiovascular disease (CVD), including the plasma concentration ...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-20114 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Pseudomonas putida KT2442 and KT42F
Effect of inactivating the phaF gene (PP_5007) on the transcriptome of cells growing exponentially in PHA production medium
ORGANISM(S): Pseudomonas putida 
2010-12-01 | E-MEXP-2970 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse spermatagonia stimulated with kit ligand, bone morphogenetic protein 4 (BMP4) or all-trans retinoic acid
wide genome analysis of difference in gene expression induced by treatment with kit ligand (KL), or bone mprphogenetic protein 4 (BMP4), or all-trans retinoic acid in spermatogonia from 7-day-old mice, using Mouse Genome 430 2.0 Array from Affymetrix, representing approximately 45000 mouse known gen...
ORGANISM(S): Mus musculus 
2007-08-01 | E-MEXP-1126 | biostudies-arrayexpress
TranscriptomicsGene expression and DNA methylation of lung tumors in Dnmt3a deficient vs. WT mice
This SuperSeries is composed of the following subset Series: GSE32415: Mouse lung tumor tissue: Dnmt3a KO vs. Dnmt3a WT GSE32484: DNA methylation of dnmt3a deficient Kras lung tumors and dnmt3a wt Kras lung tumors Refer to individual Series
ORGANISM(S): Mus musculus 
2011-10-25 | E-GEOD-32487 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat insulinoma-beta (INS-1E) cells exposed to the cytokines IL-1-beta and IFN-gamma for six different lengths of time and with or without the inducible NO synthase blocker NMA
Locally released cytokines contribute to beta cell dysfunction and apoptosis in Type 1 diabetes. In vitro exposure of insulin producing INS-1E cells to the cytokines interleukin (IL)-1beta + interferon (IFN) gamma leads to a significant increase in apoptosis. To characterize the genetic networks im...
ORGANISM(S): Rattus norvegicus 
2006-06-14 | E-CBIL-10 | biostudies-arrayexpress
TranscriptomicsCharacterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.
To identify genes expressed during initiation of lung organogenesis, we generated transcriptional profiles of the prospective lung region of the mouse foregut (mid-foregut) microdissected from embryos at three developmental stages between embryonic day 8.5 (E8.5) and E9.5. This period spans from lun...
ORGANISM(S): Mus musculus 
2010-01-14 | E-GEOD-19873 | biostudies-arrayexpress
TranscriptomicsMouse lung tumor tissue: Dnmt3a KO vs. Dnmt3a WT
Transcriptional profiling of mouse lung tumors comparing Dnmt3a KO/K-ras G12D mutant with Dnmt3a WT/K-ras G12D mutant. The goal is to search for the difference of mRNA abundance between Dnmt3a KO and WT tumors. Two-condition experiment, KO vs. WT tissure. Biological replicates: 12.
ORGANISM(S): Mus musculus 
2011-10-25 | E-GEOD-32415 | biostudies-arrayexpress
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