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TranscriptomicsGene expression data for worker honey bees experimentally exposed to a dual infection with Deformed wing virus and Nosema ceranae.
Bees from 3 unrelated colonies were injected with 1ul PBS extract containing 10^9 genome equivalent of Deformed wIng virus (DWV) and/or fed 10µl sucrose solution containing 10^5 fresh Nosema ceranae spores. Control bees were injected and fed with an equivalent DWV- and Nosema-free extract respectiv...
ORGANISM(S): Apis mellifera 
2017-03-08 | E-MTAB-5508 | biostudies-arrayexpress
TranscriptomicsEffects of moderate ethanol consumption during pregnancy on placental gene expression
We conducted a preliminary investigation to determine whether ethanol-induced alterations in placental gene expression may have some utility as a diagnostic indicator of maternal drinking during pregnancy as well as a prognostic indicator of risk for adverse neurobehavioral outcomes in affected offs...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-18162 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brains of 10 day old virgin queen, sterile worker, and reproductive worker honey bees
We used microarrays to monitor expression patterns of several thousand genes in the brains of same-aged (10 day old) virgin queens, sterile workers, and reproductive workers in honey bees (Apis mellifera).
ORGANISM(S): Apis mellifera 
2008-07-29 | E-MEXP-1044 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in wild-type Drosophila testes with tbrd-1 mutant testes
Gene expression is tightly linked to histone acetylation on lysine residues that can be recognized by bromodomains. The testis-specific bromodomain protein tBRD-1 is essential for male fertility and might act as a co-factor of testis-specifc TAFs. Here, we perform microarray analyses and demonstrate...
ORGANISM(S): Drosophila melanogaster 
2014-08-08 | E-GEOD-52511 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of QMP pheromone-mediated gene expression in the honey bee brain
This experiment was designed to monitor the gene expression changes of young bees raised with and without queen mandibular pheromone (QMP). This experiment was a timecourse, comparing QMP- to QMP+ bees over 4 days of exposure. Bees that had eclosed over 16 hours were collected from a brood frame a...
ORGANISM(S): Apis mellifera 
2004-05-01 | E-MEXP-79 | biostudies-arrayexpress
TranscriptomicsComparison of Holstein and Jersey day 6 embryos
Some embryos display better survival potential to cryopreservation than others. The cause of such phenotype is still unclear and might be due to cell damage during cryopreservation, resulting from over-accumulation and composition of lipids. In cattle embryos, in vitro culture conditions have been s...
ORGANISM(S): Bos taurus 
2014-10-22 | E-GEOD-62553 | biostudies-arrayexpress
ProteomicsProteomic diversity in bacteria: Insights and implications for bacterial identification
We acquired the largest bacterial proteomic resource, covering 303 species, 119 genera, and five phyla. The proteome coverage is, on average, over 50%. Additionally, we acquired further datasets for bacterial identification algorithm validation: i) 303 species at a 30-minute gradient (38 samples per...
ORGANISM(S): Bacteria (ncbitaxon:2) 
2024-12-06 | MSV000096603 | MassIVE
TranscriptomicsGenome-Wide Gene Expression Profiling Of Chicken Spleen Responding To Campylobacter jejuni Infection In Broilers
Campylobacter jejuni (C. jejuni) is a zoonotic pathogen that causes human diarrhea worldwide. Chickens are a natural reservoir of C. jejuni. Understanding the host response to C. jejuni infection at the molecular level will lay the foundation to control human campylobacterosis by reducing food conta...
ORGANISM(S): Gallus gallus 
2011-01-01 | E-GEOD-18541 | biostudies-arrayexpress
ProteomicsPrion MRM assay development and clinical study
Therapies currently in preclinical development for prion disease seek to lower prion protein (PrP) expression in the brain. Trials of such therapies are likely to rely on quantification of PrP in cerebrospinal fluid (CSF) as a pharmacodynamic biomarker and possibly as a trial endpoint. Studies using...
ORGANISM(S): Homo Sapiens Rattus Norvegicus Mus Musculus Macaca Fascicularis 
2019-11-19 | PXD014781 | panorama
MetabolomicsMetabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
Untargeted metabolomics has the potential to improve the predictivity of in vitro toxicity models and therefore may aid the reduction of expensive and laborious animal models. Here we describe a chronic nephrotoxicity study conducted on a human renal proximal tubular epithelial cell line (RPTEC/TERT...
2015-09-07 | MTBLS140 | MetaboLights
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