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GenomicsSingle cell RNA-seq Analysis of Wild Type(WT), Dcaf11 knockout(KO) and Dcaf11 knockdown(KD) embryos
Single cell RNA-seq Analysis of Wild Type(WT), Dcaf11 knockout(KO) and Dcaf11 knockdown(KD) embryos
PRJNA548909 | ENA
ProteomicsDCAF11-dependent molecular glue degrader activated by glutathionylation
Targeted protein degradation is a powerful pharmacological strategy that harnesses the ubiquitin proteasome system to eliminate disease-relevant proteins, including otherwise undruggable proteins. Here, we report an unbiased and broadly applicable platform for the systematic discovery of molecular g...
ORGANISM(S): Homo sapiens (Human) 
2026-06-18 | PXD067063 | Pride
E3 ligase Ddx18 Molecular glue Protein degradation Dcaf11 Gluthionylation 
ProteomicsDCAF11-dependent molecular glue degrader activated by glutathionylation
Targeted protein degradation is a powerful pharmacological strategy that harnesses the ubiquitin proteasome system to eliminate disease-relevant proteins, including otherwise undruggable proteins. Here, we report an unbiased and broadly applicable platform for the systematic discovery of molecular g...
ORGANISM(S): Homo sapiens (Human) 
2026-06-18 | PXD067066 | Pride
E3 ligase Ddx18 Molecular glue Protein degradation Dcaf11 Gluthionylation 
ProteomicsDCAF11-dependent molecular glue degrader activated by glutathionylation
Targeted protein degradation is a powerful pharmacological strategy that harnesses the ubiquitin proteasome system to eliminate disease-relevant proteins, including otherwise undruggable proteins. Here, we report an unbiased and broadly applicable platform for the systematic discovery of molecular g...
ORGANISM(S): Homo sapiens (Human) 
2026-06-18 | PXD067070 | Pride
E3 ligase Ddx18 Molecular glue Protein degradation Dcaf11 Gluthionylation 
ProteomicsDCAF11-dependent molecular glue degrader activated by glutathionylation
Targeted protein degradation is a powerful pharmacological strategy that harnesses the ubiquitin proteasome system to eliminate disease-relevant proteins, including otherwise undruggable proteins. Here, we report an unbiased and broadly applicable platform for the systematic discovery of molecular g...
ORGANISM(S): Homo sapiens (Human) 
2026-06-18 | PXD067016 | Pride
E3 ligase Ddx18 Molecular glue Protein degradation Dcaf11 Gluthionylation 
ProteomicsDCAF11-dependent molecular glue degrader activated by glutathionylation
Targeted protein degradation is a powerful pharmacological strategy that harnesses the ubiquitin proteasome system to eliminate disease-relevant proteins, including otherwise undruggable proteins. Here, we report an unbiased and broadly applicable platform for the systematic discovery of molecular g...
ORGANISM(S): Homo sapiens (Human) 
2026-06-18 | PXD067067 | Pride
E3 ligase Ddx18 Molecular glue Protein degradation Dcaf11 Gluthionylation 
GenomicsRNA-seq Analysis of Wild Type(WT) and Dcaf11 overexpression (OE) ESCs
RNA-seq Analysis of Wild Type(WT) and Dcaf11 overexpression (OE) ESCs
PRJNA747277 | ENA
TranscriptomicsSingle cell RNA-seq Analysis of Wild Type(WT), Dcaf11 knockout(KO) and Dcaf11 knockdown(KD) embryos
Telomeres play vital roles in ensuring chromosome stability and are thus closely linked with the onset of aging and human disease. Telomeres undergo extensive lengthening during early embryogenesis through the so-called alternative lengthening of telomere (ALT) mechanism. However, the detailed molec...
ORGANISM(S): Mus musculus 
2021-01-01 | GSE132745 | GEO
GenomicsKap1 ChIP-seq Analysis of Wild Type(WT) and Dcaf11 overexpresion(OE) ESCs
Kap1 ChIP-seq Analysis of Wild Type(WT) and Dcaf11 overexpresion(OE) ESCs
PRJNA681174 | ENA
GenomicsULI-NChIP-seq Analysis of Wild Type(WT) and Dcaf11 overexpresion(OE) ESCs [ChIP-seq]
ULI-NChIP-seq Analysis of Wild Type(WT) and Dcaf11 overexpresion(OE) ESCs [ChIP-seq]
PRJNA669690 | ENA
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