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MetabolomicsAberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Xenograft assays)

Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by which different molecular subgroups of GBM exp...

2022-11-08 | MTBLS730 | MetaboLights
MetabolomicsAberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Stem cell and cell line assays)

Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by which different molecular subgroups of GBM exp...

2022-11-08 | MTBLS4708 | MetaboLights
TranscriptomicsRNA-seq analysis reveals significant effects of EGFR signaling on mesenchymal stem cells (MSC)
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goal of this study is to analyse the whole transcriptome of MSCs stimulated with TGFα in order to comprehensively assess the genes regulated by EGFR signalling Methods: Libraries of cDNA wer...
ORGANISM(S): Homo sapiens 
2015-06-26 | E-GEOD-60560 | biostudies-arrayexpress
TranscriptomicsAtrial Myxomas Arise From Multipotent Myxoid Cardiac Stem Cells
Myxomas, the most common primary tumor of the heart, usually develop in the atria and consist of a myxoid matrix composed of an acid-mucopolysaccharide-rich stroma with polygonal stromal cells scattered throughout the matrix. These benign tumors, despite their rarity, are a research focus because of...
ORGANISM(S): Homo sapiens 
2020-05-02 | E-MTAB-8642 | biostudies-arrayexpress
TranscriptomicsAtrial Myxomas Arise From Multipotent Myxoid Cardiac Stem Cells
Myxomas, the most common primary tumor of the heart, usually develop in the atria and consist of a myxoid matrix composed of an acid-mucopolysaccharide-rich stroma with polygonal stromal cells scattered throughout the matrix. These benign tumors, despite their rarity, are a research focus because of...
ORGANISM(S): Homo sapiens 
2020-04-01 | E-MTAB-8701 | biostudies-arrayexpress
UnknownRepurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
Not available
S-SCDT-EMM-2020-13742 | biostudies-other
UnknownMiR-182-3p targets TRF2 and impairs tumor growth of triple negative breast cancer
Not available
S-SCDT-10_15252-EMMM_202216033 | biostudies-other
UnknownThe impact of vaccination status on post-acute sequelae in hospitalized COVID-19 survivors using a multi-disciplinary approach: An observational single center study.
Not available
S-EPMC11617281 | biostudies-literature
UnknownErgonomics in the operating room and surgical training: a survey on the Italian scenario.
Not available
S-EPMC11337608 | biostudies-literature
UnknownThe role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic.
Not available
S-EPMC10513414 | biostudies-literature
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