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UnknownThe risks associated with percutaneous native kidney biopsies: a prospective study.

Background

The known risks and benefits of native kidney biopsies are mainly based on the findings of retrospective studies. The aim of this multicentre prospective study was to evaluate the safety of percutaneous renal biopsies and quantify biopsy-related complication rates in Italy.

Met...

S-EPMC9976765 | biostudies-literature
UnknownUPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Bronchiolitis is an acute respiratory illness that is the leading cause of hospitalization in young children. This document aims to update the consensus document published in 2014 to provide guidance on the current best practices for managing bronchiolitis in infants. The document addresses care in ...
S-EPMC9912214 | biostudies-literature
UnknownIdentification of p53-target genes in Danio rerio.
To orchestrate the genomic response to cellular stress signals, p53 recognizes and binds to DNA containing specific and well-characterized p53-responsive elements (REs). Differences in RE sequences can strongly affect the p53 transactivation capacity and occur even between closely related species. T...
S-EPMC5007497 | biostudies-literature
UnknownLong-term effectiveness, safety, and liver stiffness dynamics of PBC treatment with obeticholic acid in real-world.

Background & aims

Several studies have assessed the short-term effectiveness and safety of obeticholic acid (OCA) in the real-world setting. We aimed to extend knowledge on the real-world effectiveness and safety of OCA treatment by expanding sample size and follow-up, and by exploring chang...
S-EPMC12276448 | biostudies-literature
UnknownA C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.
The G4C2-repeat expansion in C9orf72 is the most common known cause of amyotrophic lateral sclerosis and frontotemporal dementia. The high phenotypic heterogeneity of C9orf72 patients includes a wide range in age of onset, modifiers of which are largely unknown. Age of onset could be influenced by e...
S-EPMC6158742 | biostudies-literature
UnknownEvaluating the Protective Effect of Intravesical Bacillus Calmette-Guerin against SARS-CoV-2 in Non-Muscle Invasive Bladder Cancer Patients: A Multicenter Observational Trial.
We aim to evaluate the potential protective role of intravesical Bacillus Calmette-Guerin (BCG) against SARS-CoV-2 in patients with non-muscle invasive bladder cancer (NMIBC). Patients treated with intravesical adjuvant therapy for NMIBC between January 2018 and December 2019 at two Italian referral...
S-EPMC10000457 | biostudies-literature
UnknownSafety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part Phase Ib/II study.
Not available
S-EPMC7387307 | biostudies-literature
UnknownSARS-CoV-2 infection and acute ischemic stroke in Lombardy, Italy.

Objective

To characterize patients with acute ischemic stroke related to SARS-CoV-2 infection and assess the classification performance of clinical and laboratory parameters in predicting in-hospital outcome of these patients.

Methods

In the setting of the STROKOVID study including pa...
S-EPMC8142879 | biostudies-literature
UnknownColorectal Cancer with Peritoneal Metastases: The Impact of the Results of PROPHYLOCHIP, COLOPEC, and PRODIGE 7 Trials on Peritoneal Disease Management.
HIPEC is a potentially useful locoregional treatment combined with cytoreduction in patients with peritoneal colorectal metastases. Despite being widely used in several cancer centers around the world, its role had never been investigated before the results of three important RCTs appeared on this t...
S-EPMC9818482 | biostudies-literature
UnknownImpact of SARS-CoV-2 on reperfusion therapies for acute ischemic stroke in Lombardy, Italy: the STROKOVID network.
Whether and how SARS-CoV-2 outbreak affected in-hospital acute stroke care system is still matter of debate. In the setting of the STROKOVID network, a collaborative project between the ten centers designed as hubs for the treatment of acute stroke during SARS-CoV-2 outbreak in Lombardy, Italy, we r...
S-EPMC7937781 | biostudies-literature
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