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Authors: Marc P. Forrest1,2, Marc Dos Santos1,2, Nicolas H. Piguel1,2, Yi-Zhi Wang3, Nicole A. Hawkins4, Vikram A. Bagchi1,2, Leonardo E. Dionisio1,2, Sehyoun Yoon1,2, Dina Simkin3,4, Maria Dolores Martin-de-Saavedra1,2, Ruoqi Gao1,2, Katherine E. Horan1,2, Alfred L. George Jr.2,4, Mark S. LeDoux5,6...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-12-12 | MSV000090884 | MassIVE

Three-dimensional (3D) cell culture technologies, which more closely mimic the complex microenvironment of tissue, are being increasingly evaluated as a tool for the preclinical screening of clinically promising new molecules, and studying of tissue metabolism. Studies of metabolites released int...

2023-12-12 | MTBLS5375 | MetaboLights
The presence of melanopsin (OPN4) has been shown in cultured murine melanocytes and was associated with ultraviolet A radiation (UVA) reception. We demonstrated the protective role of OPN4 in skin physiology and the increased UVA-induced damage in its absence using proteomics analysis.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-03-29 | MSV000091592 | MassIVE
The goal of this study was to evaluate the role of OPN4 in melanoma development using in vitro, in vivo, and proteomics approaches.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-17 | MSV000088579 | MassIVE
Coenzyme Q10 deficiency syndrome includes a clinically heterogeneous group of mitochondrial diseases characterized by low content of CoQ10 in tissues. The only currently available treatment is supplementation with CoQ10, which improves the clinical phenotype in some patients but does not reverse est...
ORGANISM(S): Homo sapiens 
transriptional profiling of Bacillus subtilis treated with Plectasin
ORGANISM(S): Bacillus subtilis strain 168 
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