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TranscriptomicsExpression in the dorsal telencephalon of E13.5 conditional Dicer KO mice
To study the effect of miRNA depletion in the embryonic forebrain, we isolated RNA from E13.5 dorsal telencephalon of mice homozygous for a floxed Dicer allele and hemizygous for the forebrain expressed Emx1Cre (Dicer KO mice). These samples were compared to littermates heterozygous for the floxed a...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-37610 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in Dicer knock-out mice
The precise mechanisms by which microRNAs (miRNAs) contribute to the dynamic regulation of gene expression during forebrain development are still partly elusive. Here we show that depletion of miRNAs via genetic inactivation of Dicer after the onset of forebrain neurogenesis profoundly impairs the m...
ORGANISM(S): Mus musculus 
2012-11-14 | E-MTAB-1062 | biostudies-arrayexpress
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