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TranscriptomicsExpression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer
Macrophages represent an important component of the tumor microenvironment and play a complex role in cancer progression. These cells are characterized by a high degree of plasticity, and alter their phenotype in response to local environmental cues. While the M1/M2 classification of macrophages has...
ORGANISM(S): Mus musculus 
2016-03-02 | E-GEOD-76033 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling in primary Diffuse Large B cell Lymphoma (DLBCL) and normal Germinal Center B Cells
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study we carried out genome-wide DNA methylatio...
ORGANISM(S): Homo sapiens 
2014-01-18 | E-GEOD-54200 | biostudies-arrayexpress
TranscriptomicsRecruitment of MYC to target genes in ramos and mutu3 cells
Follicular lymphomas and diffuse large B-cell lymphomas have markedly different biological phenotypes and yet all originate from mature, germinal center B-cells. We hypothesized that alterations in DNA methylation patterning might help explain the clinical heterogeneity of these diseases. We report ...
ORGANISM(S): Homo sapiens 
2012-11-27 | E-GEOD-31110 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of differentiated human blood cells: The HaemAtlas
Transcription profiling of highly purified blood cells from normal individuals
ORGANISM(S): Homo sapiens 
2009-02-06 | E-TABM-633 | biostudies-arrayexpress
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