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TranscriptomicsGene Expression in the Human Mammary Epithelium in response to consumption of high fat (H-FAT) and high carbohdyrate (H-CHO) diets.
Mammary gland (MG) de novo lipogenesis contributes significantly to milk fat in animals but little is known in humans. We hypothesized that de novo lipogenesis, as reflected by incorporation of 13C carbons from [U-13C]glucose into fatty acids (FAs) and glycerol in triglycerides (TG), will be greate...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-51874 | biostudies-arrayexpress
UnknownTransforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production.
Not available
S-EPMC5207151 | biostudies-literature
UnknownDe Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma.
Not available
S-EPMC12079101 | biostudies-literature
UnknownPathway engineered enzymatic de novo purine nucleotide synthesis.
Not available
S-EPMC2746247 | biostudies-literature
UnknownInhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.
Not available
S-EPMC6702104 | biostudies-literature
UnknownDe novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
Not available
S-EPMC6737211 | biostudies-literature
UnknownFailure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells.
Not available
S-EPMC11715087 | biostudies-literature
UnknownSerine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
Not available
S-EPMC4728077 | biostudies-literature
UnknownIdentification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria.
Not available
S-EPMC3174652 | biostudies-literature
UnknownPurine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Not available
S-EPMC9110385 | biostudies-literature
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