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TranscriptomicsGene expression data from 131 human subjects in Detroit, Michigan
Background Complex diseases are often difficult to diagnose, treat and study due to the multi-factorial nature of the underlying etiology. Large data sets are now widely available that can be used to define novel, mechanistically distinct disease subtypes (endotypes) in a completely data-driven mann...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-35571 | biostudies-arrayexpress
ProteomicsA decision tree searching strategy to boost the identification of cross-linked peptides
We describe an efficient decision tree searching strategy (DTSS) to boost the identification of cross-linked peptides. The DTSS approach allows the identification of a wealth of complementary information to facilitate the construction of more protein-protein interaction networks for human cell lysat...
ORGANISM(S): Escherichia coli 
2020-11-23 | PXD018291 | Pride
Xlink-ms Data-analysis 
ProteomicsMass Spectrometry Methods and Mathematical PK/PD Model for Decision Tree-Guided Covalent Drug Development
Covalent drug discovery efforts are growing rapidly but have major unaddressed limitations. These include high false positive rates during hit-to-lead identification; the inherent uncoupling of covalent drug concentration and effect [i.e., uncoupling of pharmacokinetics (PK) and pharmacodynamics (PD...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-23 | PXD046903 | Pride
Covalent drug discovery Als Intact protein mass spectrometry Pk/pd 
MetabolomicsRANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies

INTRODUCTION: The Metabolomics Standards Initiative has recommended four categories for metabolite assignments in NMR-based metabolic profiling studies. The putatively annotated compound category is most commonly reported by metabolomics investigators. However, there is significa...

2019-09-27 | MTBLS781 | MetaboLights
UnknownPatient decision aids: a content analysis based on a decision tree structure.
Not available
S-EPMC6642566 | biostudies-literature
UnknownA decision tree to improve identification of pathogenic mutations in clinical practice.
Not available
S-EPMC7063785 | biostudies-literature
Proteomicsalpha-lytic proteases
S. pombe proteome digested separately by four proteases and analyzed with an LTQ-Orbitrap Velos with a data-dependent decision tree method.
2013-12-23 | MSV000078516 | MassIVE
TranscriptomicsTranscription profiling of acute lymphoblastic leukaemia patient samples that represent six different subgroups defined by cytogenetic features and immunophenotype
We examined published microarray data from 104 acute lymphoblastic leukaemia patient specimens, that represent six different subgroups defined by cytogenetic features and immunophenotypes. Using the decision-tree based supervised learning algorithm Random Forest (RF), we determined a small set of ge...
ORGANISM(S): Homo sapiens 
2007-05-11 | E-TABM-125 | biostudies-arrayexpress
UnknownDecision tree model for predicting ovarian tumor malignancy based on clinical markers and preoperative circulating blood cells.
Not available
S-EPMC11844102 | biostudies-literature
UnknownBayesian network models with decision tree analysis for management of childhood malaria in Malawi.
Not available
S-EPMC8130361 | biostudies-literature
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