Decoy-free framework

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New mixture models for decoy-free false discovery rate estimation in mass-spectrometry proteomics

We introduce a new decoy-free framework for false discovery rate (FDR) estimation that generalizes present decoy-free approaches (DFAs) while exploiting more search data in a manner similar to target-decoy approaches (TDAs).

ORGANISM(S): Homo sapiens (Human)

2020-01-10 | PXD020322 | Pride

New mixture models for decoy-free false discovery rate estimation in mass spectrometry proteomics.

Not available

S-EPMC7773488 | biostudies-literature

An algorithm for decoy-free false discovery rate estimation in XL-MS/MS proteomics.

Not available

S-EPMC11256928 | biostudies-literature

Balancing multiple objectives in conformation sampling to control decoy diversity in template-free protein structure prediction.

Not available

S-EPMC6485169 | biostudies-literature

Decoy selection for protein structure prediction via extreme gradient boosting and ranking.

Not available

S-EPMC7724862 | biostudies-literature

Systematic Discovery of Structural Elements Governing Mammalian mRNA Stability

Decoding post-transcriptional regulatory programs underlying gene expression is a crucial step toward a predictive dynamical understanding of cellular state transitions. Despite recent systematic efforts, the sequence determinants of such mechanisms remain largely uncharacterized. An important obsta...

ORGANISM(S): Homo sapiens

2012-02-28 | E-GEOD-35800 | biostudies-arrayexpress

Query Mix-Max Method for FDR Estimation Supported by Entrapment Queries.

Not available

S-EPMC11894652 | biostudies-literature

The Female Perspective of Personality in a Wild Songbird: Repeatable Aggressiveness Relates to Exploration Behaviour.

Not available

S-EPMC5550452 | biostudies-literature

A potential role of Gsdf-eEF1 complex in inhibiting germ cell proliferation: A protein interaction analysis in medaka (Oryzias latipes) from a proteomics perspective

Gonadal soma-derived factor (gsdf) has been demonstrated as essential for testicular differentiation in medaka (Oryzias latipes). To understand the protein dynamics of Gsdf in spermatogenesis regulation, we used a His-tag “pull-down” assay coupled with shotgun LC-MS/MS to identify a group of potenti...

ORGANISM(S): Oryzias latipes (Japanese rice fish) (Japanese killifish)

2020-12-09 | PXD022153 | Pride

Gsdf eef1 42sp50

A new generation of statistical potentials for proteins.

Not available

S-EPMC1459517 | biostudies-literature

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