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Little is known about the epigenomics of liposarcoma (LPS). Here, we profiled the global expression of 9 epigenetic marks in well differentiated (WD) and dedifferentiated (DD) LPS from 151 patients and found increased H3K9me3 among DDLPS tumors. We performed ChIP-seq and gene expression profiling ...
ORGANISM(S): Homo sapiens 
Little is known about the epigenomics of liposarcoma (LPS). Here, we profiled the global expression of 9 epigenetic marks in well differentiated (WD) and dedifferentiated (DD) LPS from 151 patients and found increased H3K9me3 among DDLPS tumors. We performed ChIP-seq and gene expression profiling ...
ORGANISM(S): Homo sapiens 
Pancreatic acinar cells can dedifferentiate upon tissue injury and acquire ductal characteristics. This acquisition of duct cell features is critical in tumor development. Nevertheless, duct cells themselves are less prone for development of PDAC (pancreatic ductal adenocarcinoma) than dedifferentia...
ORGANISM(S): Homo sapiens 
We performed microRNA microarray analysis to determine microRNAs that are differentially expressed between the differentiated hfRPE monolayer (pigmented, hexagonally packed) and dedifferentiated hfRPE cells (non-pigmented, fibroblast-like). Experiment was performed using the Agilent-019118 Human miR...
ORGANISM(S): Homo sapiens 
Genomic characterization of well differentiated/dedifferentiated retroperitoneal liposarcoma
Methylation profiling of dedifferentiated chondrosarcoma (DDCS) samples
RNA-seq of purified human pancreatic dedifferentiated acinar cells and duct cells
Cellular origin and clonal evolution of human dedifferentiated liposarcoma
Cellular origin and clonal evolution of human dedifferentiated liposarcoma
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