Sort   by:  
 Page size 
ProteomicsHuman Sumoylome (SUMO-2) upon bacterial infection
Given the role of SUMOylation in pathogenic infection, we wanted to evaluate the changes to the host SUMO-2 subproteome during Shigella infection. HeLa cells overexpressing TAP-SUMO-2 or TAP-empty were used in conjunction with SILAC (Stable Isotope Labeling of Amino acids in Culture) (Golebiowski ...
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD001100 | Pride
Human Sumo-2 Shigella flexneri Hela Tap tag 
TranscriptomicsQuantitative analysis of proliferative and Ras-induced senescent human primary fibroblasts transcriptomes
The goals of this study is to analyse transcriptionnal changes in senescent cells and to compare them with ChIPseq data for several histones marks and proteins of the SUMO machinery mRNA profiling of proliferative versus Ras-induced senescent humain primary fibroblasts 5 days post-infection
ORGANISM(S): Homo sapiens 
2013-07-24 | E-GEOD-42212 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human hepatocellular carcinoma samples shows miR-221 overexpression contributes to liver tumorigenesis
We profiled miRNA expression in tissue samples (104 HCC, 90 adjacent cirrhotic livers, 21 normal livers) as well as in 35 HCC cell lines. A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93,miR-96, and let-7c) was linked to disease progression from normal liver through cirrh...
ORGANISM(S): Homo sapiens 
2009-12-08 | E-TABM-866 | biostudies-arrayexpress
GenomicsH3K4me3 chromatin profiling in SUMOylation-competent and -deficient bone marrow derived dendritic cells unstimulated or stimulated with LPS
Purpose: To determine H3K4me3 chromatin profile in UBC9WT and UBC9KO BMDC before and after LPS stimulation. Methods: H3K4me3 chromatin profile was determined by sequencing UBC9 WT and UBC9 KO BMDC chromatin immunoprecipitated with antibody specific for H3K4me3. Results: We show differential chromati...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-66338 | biostudies-arrayexpress
GenomicsSUMO and RNAPolII chromatin profiling in SUMOylation-competent and -deficient bone marrow derived dendritic cells unstimulated or stimulated with LPS
Purpose: To determine SUMO1 and SUMO2 chromatin profile in a static and dynamic manner in BMDC before and after LPS stimulation, and to determine RNAPolII chromatin occupancy in sumoylation-deficient BMDC compared to wild-type cells. Methods: SUMO1, SUMO2 and RNAPolII chromatin profiles were determi...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-66315 | biostudies-arrayexpress
TranscriptomicsIdentification of p53-regulated microRNAs in Hapatocellular Carcinoma (HCC).
p53 suppresses tumor progression and metastasis by regulating a large set of genes and microRNAs. By profiling 92 primary hepatocellular carcinomas (HCCs) and 9 HCC cell lines, we found that p53 upregulates microRNAs including miR-200 and miR-192 family members. By sequencing TP53 in 92 HCC samples,...
ORGANISM(S): Homo sapiens 
2011-05-11 | E-GEOD-28661 | biostudies-arrayexpress
GenomicsGenome wide occupancy of SUMO machinery in proliferative and Ras-induced senescent human primary fibroblasts
Transcription factors represent one of the largest groups of proteins regulated by SUMO, and their modification has generally been correlated with transcriptional repression. However, as most of the studies focus on specific sumoylated transcriptional regulators, the distribution and global role of ...
ORGANISM(S): Homo sapiens 
2013-07-24 | E-GEOD-42211 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of human metastatic breast cancer
metastatic breast cancer miRNA
ORGANISM(S): Homo sapiens 
2010-06-02 | E-TABM-971 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human acute myeloid leukemia samples
AML
ORGANISM(S): Homo sapiens 
2010-05-10 | E-TABM-972 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human ovarian carcinoma samples
OVARIAN EPITHELIAL CARCINOMA
ORGANISM(S): Homo sapiens 
2010-05-10 | E-TABM-975 | biostudies-arrayexpress
Sort   by:  
 Page size