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MetabolomicsLinking genetic, metabolic and phenotypic diversity 1 among S. cerevisiae strains using multi-omics associations
The selection of bioengineering platform strains and engineering strategies to improve the stress resistance of Saccharomyces cerevisiae remains a pressing need in bio-based chemical production. Thus, a systematic effort to exploit the genotypic and phenotypic diversity to boost yeast’s industrial v...
2019-01-16 | MTBLS780 | MetaboLights
ProteomicsProfiling Yeast Deletion Strains using Sample Multiplexing and Network-based Analyses
The yeast, Saccharomyces cerevisiae, is a widely used model system for investigating conserved biological functions and pathways. Advancements in sample multiplexing have facilitated the study of the yeast proteome, yet many yeast proteins remain uncharacterized or only partially characterized. The ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-02 | PXD032042 | Pride
Deletion strains Yko Rts-ms3 Yeast Tmtpro 
TranscriptomicsTranscription profiling of yeast homozygous and essential heterozygous diploid deletion strains screened with 3-nitroso-imidazo[1,2-a]pyridines and -pyrimidines to identify gene deletions that confer sensitivity to each compound
The complete pool of barcoded homozygous and essential heterozygous diploid deletion strains of S. cerevisiae were screened with 3-nitroso-imidazo[1,2-a]pyridines and -pyrimidines to identify gene deletions that confer sensitivity to each compound.
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-19 | E-TABM-560 | biostudies-arrayexpress
ProteomicsTargeted proteome analysis of the central carbon metabolism related enzymes in S. cerevisiae mutant strains
Expression profiles of 110 the central metabolism-related enzymes were obtained by the selected reaction monitoring (SRM) assay methods using LC-MS/MS from the wild type (BY4742), a GCR2 gene deletion strain, and 29 single-gene deletion strains lacking enzyme genes responsible for central carbon met...
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast) 
2017-03-22 | PXD004714 | JPOST Repository
ProteomicsEvaluating Protein Extraction Techniques for Elucidating Proteomic Changes in Yeast Deletion Strains
Alterations in protein abundance profiles in yeast deletion strains are frequently utilized to gain insights into cellular functions and regulatory networks, most of which are conserved in higher eukaryotes. Here, we investigate the impact of protein extraction methodologies on proteomic analysis of...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-08-04 | PXD063969 | Pride
Protein extraction Bead-based lysis Sumoylation Mass spectrometry Gene deletion Yeast proteomics 
TranscriptomicsTranscriptomic analysis of fungus Penicillium decumbens and brlA deletion strains in different culture medium
Transcriptomic analysis of fungus Penicillium decumbens and brlA deletion strains in liquid medium and solid medium respectivelly Examination of differential gene expressions by Penicillium decumbens strains 114-2 and brlA deletion stains in liquid medium and solid medium
ORGANISM(S): Penicillium decumbens 
2013-04-09 | E-GEOD-45855 | biostudies-arrayexpress
TranscriptomicsVariation in the Genomic islands of porcine enteropathogenic E. coli strains of serogroup O45 revealed by CGH and PCR.
Background: Members of E. coli serogroup O45 are porcine enteropathogenic E. coli (PEPEC) strains which cause post-weaning diarrhea and produce characteristic attaching and effacing (A/E) lesions. Most of O45 PEPEC strains possess the locus of enterocyte effacement (LEE), encoding the virulence fact...
ORGANISM(S): Escherichia coli 
2010-05-16 | E-GEOD-17036 | biostudies-arrayexpress
TranscriptomicsCross talk between the cell wall integrity and cAMP/protein kinase A pathways in Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen of immunocompromised people that causes fatal meningitis. The fungal cell wall is essential to viability and pathogenesis of C. neoformans, and biosynthesis and repair of the wall is primarily controlled by the cell wall integrity (CWI) signaling pathwa...
ORGANISM(S): Cryptococcus neoformans 
2014-07-01 | E-GEOD-57217 | biostudies-arrayexpress
GenomicsTranscription analysis of SEC72 deletion strains
Transcription analysis of SEC72 deletion strains
PRJEB66513 | ENA
Transcriptomicswt expression changes in deletion strain-conditioned media
To rule out expression changes caused by depletion from, or excretion into the media, wild-type yeast was transferred to filtered media in which slow-growing deletion strains were grown previously
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-14 | E-MTAB-2218 | biostudies-arrayexpress
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