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ProteomicsComparative proteomics of Mycoplasma pneumoniae clinical isolates
The human respiratory tract pathogen M. pneumoniae is one of the best characterized minimal bacterium. Until now, two main groups of clinical isolates of this bacterium have been described (types 1 and 2), differing in the sequence of the P1 adhesin gene. Here, we have sequenced the genomes of 23 cl...
ORGANISM(S): Mycoplasma pneumoniae M129-B7 
2016-07-05 | PXD002501 | Pride
Proteomics Mycoplasma pnemoniae 
ProteomicsDefining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium
Identifying all essential genomic components is critical for the assembly of minimal artificial life. In the genome-reduced bacterium Mycoplasma pneumoniae, we found, that small ORFs (smORFs; <100 residues), accounting for 10% of all ORFs, are the most frequently essential genomic components (53%)....
ORGANISM(S): Mycoplasma pneumoniae M29 
2015-03-03 | PXD001611 | Pride
Minimal genome Small proteins Non-coding rnas 
UnknownPerspectives of women living with type 1 diabetes regarding preconception and antenatal care: A qualitative evidence synthesis.
Not available
S-EPMC10726142 | biostudies-literature
TranscriptomicsIntegration of BRCA1-mediated miRNA and mRNA signatures reveal miR-146a, miR-99b and miR-205 regulation of the TRAF2 and NFkB pathways (mRNA dataset)
BRCA1 deregulation is a frequent event in the pathogenesis of breast as well as other cancers. In addition to the DNA repair functions of BRCA1, it is involved in a wide range of cellular processes such as cell cycle, chromatin remodeling or transcription. However, the molecular events underlying BR...
ORGANISM(S): Homo sapiens 
2011-12-24 | E-GEOD-30821 | biostudies-arrayexpress
UnknownSynthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines.
Not available
S-EPMC3874341 | biostudies-literature
TranscriptomicsMolecular Signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17-AAG, in breast cancer.
We have done transcriptional profiling of 17-AAG treated (24h, 48H) breast cancer cell lines to understand the mechanisms of the drug action and indicate novel set of pharmacodynamic biomarkers of the drug response as well as of resistance Two-condition experiment, Untreated vs. Treated sensitive c...
ORGANISM(S): Homo sapiens 
2010-10-11 | E-GEOD-23209 | biostudies-arrayexpress
TranscriptomicsTumor microRNA expression profiling identifies circulating microRNAs for earlier breast cancer detection
Due to their role in tumorigenesis and remarkable stability in body fluids, microRNAs (miRNAs) are emerging as a promising diagnostic tool. The aim of this study was to identify tumor miRNA signatures for the discrimination of breast cancer and the intrinsic molecular subtypes, and the study in plas...
ORGANISM(S): Homo sapiens 
2015-09-03 | E-GEOD-58606 | biostudies-arrayexpress
UnknownPreventing respiratory illness in cerebral palsy: Results of a pilot randomized controlled trial.
Not available
S-EPMC12169566 | biostudies-literature
UnknownNavigating from phenotypic screen to clinical candidate: selective targeting the NLRP3 inflammasome
Not available
S-SCDT-10_1038-S44321-024-00181-4 | biostudies-other
UnknownMonitoring Indicators of Universal Access to Accessible and Safe Anesthetic and Surgical Care in a Peruvian Region: An Ambispective Study.
Not available
S-EPMC10118244 | biostudies-literature
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