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ProteomicsIntegrated small RNA, mRNA and protein omics reveal a miRNA network orchestrating metabolic maturation of the developing human heart
As the fetal heart develops, cardiomyocyte proliferation potential decreases while fatty acid oxidative capacity increases, a highly regulated transition known as cardiac maturation. Small noncoding RNAs, such as microRNAs (miRNAs), contribute to the establishment and control of tissue-specific tran...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD044936 | Pride
Lc-msms Human fetal heart 
TranscriptomicsGene expression profile of right ventricles from adult wild type and Ezh2-deficient hearts
Adult-onset diseases can be associated with in utero events, but mechanisms for this remain unknown. The polycomb histone methyltransferase, Ezh2, stabilizes transcription by depositing repressive marks during development that persist into adulthood, but its function in postnatal organ homeostasis i...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-34274 | biostudies-arrayexpress
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