Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human CD* T lymphocytes overexpressing hTERT
Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 a...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5143 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD8 T lymphocytes from two healthy donors transduced with hTERT
Expression in GFP vs. GFP/hTERT transduced CD8 T Lymphocytes from Healty Donors (HD) 1 and 2 at early and late passages. Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were p...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5144 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gulahuman CD8 T lyphocytes overexpressing hTERT to investigate regulation of profileration
Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 a...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5142 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human non-tumoral Formalin-Fixed Paraffin Embedded colon samples, either positive or negative to diverticulosis
Gene expression profiles from anonymous, non-tumoral Formalin-Fixed Paraffin Embedded colon samples, either positive or negative to diverticulosis. Samples were obtained from a Biobank hosted at the Centre Hospitalier Universitaire Vaudois (CHUV), to serve as reference pool for comparison with colon...
ORGANISM(S): Homo sapiens 
2013-06-21 | E-MTAB-1026 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.
Transcription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.
ORGANISM(S): Homo sapiens 
2013-06-21 | E-MTAB-990 | biostudies-arrayexpress
GenomicsA Multiplicity of Factors Contributes to Selective RNA polymerase III occupancy of a Subset of RNA polymerase III Genes in Mouse Liver
The genomic loci occupied by RNA polymerase (pol) III have been characterized in human culture cells by genome-wide chromatin immunoprecipitation experiments followed by deep sequencing (ChIP-Seq). These studies have in particular shown that only about 40 % of the annotated 622 human tRNA genes and...
ORGANISM(S): Mus musculus 
2012-01-19 | E-GEOD-33421 | biostudies-arrayexpress
TranscriptomicsA stroma-related gene signature predicts sensitivity to epirubicin-containing neoadjuvant chemotherapy in breast cancer.
The goal of the study was to identify a gene expression signature capable of predicting a pathological complete response following neoadjuvant anthracycline-based chemotherapy of breast cancer. The samples were taken from the FEC arm (5-fluorouracil, epirubicin, cyclophosphamide) of the EORTC 10994 ...
ORGANISM(S): Homo sapiens 
2008-12-19 | E-GEOD-4779 | biostudies-arrayexpress
GenomicsPROX1 ChIP-seq analysis of human colorectal cancer cells SW480R
We performed ChIP-seq data in SW480R cells. Pools of three independent ChIP experiments and input DNA were used for sequencing.
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-60390 | biostudies-arrayexpress
GenomicsGenome-wide DNA-methylation assessment by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison
DNA-methylation is an important epigenetic feature in health and disease. Two cost-efficient genome-scale methodologies to assess DNA-methylation are MethylCap-seq and Illumina's Infinium HumanMethylation450 BeadChips (HM450). However, objective information regarding the best-suited methodology for ...
EGAS00001001191 | EGA
GenomicsGenome-wide profiles of RNA polymerase II (Pol 2) DNA occupancy and the histone modifications H3K4me3 and H3K36me3 around the circadian cycle
To understand the transcriptional basis of circadian rhythms in mouse liver, we generated genome-wide profiles of RNA polymerase II (Pol 2) DNA occupancy and the histone modifications H3K4me3 and H3K36me3 around the circadian cycle. We found that Pol 2 occupancy at promoters and in gene bodies cycle...
ORGANISM(S): Mus musculus 
2012-12-06 | E-GEOD-35788 | biostudies-arrayexpress
Sort   by:  
 Page size