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ProteomicsPrenylated PALM2 Promotes the Migration of Esophageal Squamous Cancer Cells through Activating Ezrin
Proteins containing a CAAX motif at the C-terminus can occur prenylation modification and regulate the localization and activity of a series of key regulatory proteins, including RAS superfamily members, heterotrimeric G proteins, nuclear lamina protein, and several protein kinases and phosphatases....
ORGANISM(S): Homo Sapiens 
2023-03-20 | PXD040969 |
ProteomicsThe protein interaction of PALM2 in HEK 293T
We identify the protein interaction of PALM2 in HEK 293T. we find that PALM2 can promote the malignant behaviors of esophageal squamous cancer cell (ESCC). Focusing on the mechanism inside, we reveal that PALM2 promotes the migration of esophageal squamous cancer cells through activating it interact...
ORGANISM(S): Homo Sapiens 
2023-03-08 | PXD040700 |
ProteomicsLarge-scale and high-resolutionmass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting
Esophageal cancer (EC) is anaggressive cancer type without clinically relevant molecular subtypes defined, which hinders the development of effective strategies forEC treatment. Here, we reporteda large-scale, high-resolution massspectrometry-based proteomicand phosphoproteomics profiling of EC tumo...
ORGANISM(S): Trichuris Sp. Ex Homo Sapiens Jp-2011 
PXD021701 |
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