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TranscriptomicsRNA-seq of retinal organoids derived from RPGR patient-, control- and mutation-corrected-iPSC at different developmental stages
Retinitis pigmentosa (RP) is an irreversible and inherited retinopathy. RPGR mutations are the most common causes of this disease. It remains challenging to decipher the mechanism of RPGR mutation because of the lack of appropriate study models. The substitution of patient-specific diseased retina w...
ORGANISM(S): Homo sapiens 
2020-02-01 | E-MTAB-6490 | biostudies-arrayexpress
TranscriptomicsIdentification of long ncRNAs using RNA-seq in Arabidopsis
We profiled Arabidopsis transcriptom using RNA-seq. Each RNA library yielded 223-250 million 101-bp single-end reads (235M on average). Using Tophat and Cufflinks, 30,199~30,650 assembled transcripts were identified in each of 4 samples. Of them, 1340 ones were derived from intergenic regions includ...
ORGANISM(S): Arabidopsis thaliana 
2012-08-23 | E-GEOD-38612 | biostudies-arrayexpress
TranscriptomicsIdentification of CLF-regulated transcripts using strand-specific RNA-sequencing in Arabidopsis
CURLY LEAF (CLF), the major histone methyltransferase of Polycomb Repressive Complex 2 (PRC2), modifies trimethylation of histone H3 lysine 27 (H3K27me3) and mediates dynamical chromatin repression in Arabidopsis. Here we used strand specific RNA-sequencing to profile Arabidopsis transcriptomes obta...
ORGANISM(S): Arabidopsis thaliana 
2016-03-28 | E-GEOD-61545 | biostudies-arrayexpress
UnknownEfficacy of intraosseous access for trauma resuscitation: a systematic review and meta-analysis.
Not available
S-EPMC10012735 | biostudies-literature
TranscriptomicsIdentification of CLF-regulated transcripts in embryos at the mature-green stage by strand-specific RNA-sequencing in Arabidopsis
CURLY LEAF (CLF), the major histone methyltransferase of Polycomb Repressive Complex 2 (PRC2), modifies trimethylation of histone H3 lysine 27 (H3K27me3) and mediates dynamical chromatin repression in Arabidopsis. Our previous results suggested that CLF may play regulatory roles on seed size and lip...
ORGANISM(S): Arabidopsis thaliana 
2016-03-28 | E-GEOD-68080 | biostudies-arrayexpress
UnknownGinsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Not available
S-EPMC9459078 | biostudies-literature
UnknownLncRNA SNHG14 promotes OGD/R-induced neuron injury by inducing excessive mitophagy via miR-182-5p/BINP3 axis in HT22 mouse hippocampal neuronal cells.
Not available
S-EPMC7488096 | biostudies-literature
ProteomicsSIRT3 Deacetylates TFAM to Promote Mitochondrial Biogenesis
SIRT3 is a NAD+-dependent mitochondrial protein deacetylase participating in the regulation of central metabolism and mitochondrial proteostasis. SIRT3 is downregulated in clear cell renal cell carcinoma (ccRCC), a main type of renal cancers, but the function of SIRT3 in tumorigenesis and developmen...
ORGANISM(S): Homo sapiens (Human) 
2018-08-14 | PXD009110 | Pride
Proteomics Sirt3 Mitochondrial biogenesis Clear cell renal cancer Tfam acetylation 
TranscriptomicsTranscriptome profiling of siliques at 4 developmental stages in Arabidopsis
To search for the differential expressed genes during post-fertilization and embryonic development in Arabidopsis, We profiled transcriptome of siliques at 4 developmental stages using RNA-seq based on poly(A) selection. Each RNA library yielded 100 million 101-bp paired-end reads.Using Tophat and C...
ORGANISM(S): Arabidopsis thaliana 
2016-03-28 | E-GEOD-55866 | biostudies-arrayexpress
UnknownHypoxia induced exosomal circRNA promotes metastasis of Colorectal Cancer via targeting GEF-H1/RhoA axis.
Not available
S-EPMC7381736 | biostudies-literature
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