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UnknownMountains, Lakes, and Ancient Drainage Networks Sculpt the Phylogeographic Architecture of the Stream Headwater Fish <i>Acrossocheilus kreyenbergii</i> in China.
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S-EPMC12732399 | biostudies-literature
ProteomicsThe presence of HearNPV P26 in hemolymph from the virus-infected insect via liquid chromatography tandem mass spectrometry analysis
To examine whether P26 is involved in the extracellular melanization pathway, we used HearNPV and cotton bollworm as a testing system and detected the presence of HearNPV P26 in hemolymph from the virus-infected insect via liquid chromatography tandem mass spectrometry analysis. P26 was one of the m...
ORGANISM(S): Helicoverpa Armigera Nucleopolyhedrovirus G4 
2022-10-28 | PXD037784 |
ProteomicsComprehensive genome editing and signaling pathway engineering evolve potent and safe adenoviral producer cell
Dramatic attention has been drawn to adenovirus as a vehicle for vaccine and cancer therapy, due to the capabilities of annihilating tumor cells and stimulating host immune response. However, few producer cells are perfect for adenoviral manufacture. Herein, a novel genome editing strategy by CRISPR...
ORGANISM(S): Homo Sapiens 
2025-10-21 | PXD069719 |
ProteomicsDirect Evolution of Adeno-Associated Virus 5 Capsid Enables Specific Liver Tropism
Gene therapy has been thriving in recent years, as featured by general triumphs in several clinical trials to treat hemophilia. It highlights the significance of AAV mediated gene delivery to liver. AAV5 is a unique serotype with low neutralizing antibody prevalence. In this study, we generated an A...
ORGANISM(S): Adeno-associated Virus - 5 
2022-04-01 | PXD032891 |
ProteomicsIgA Nephropathy Proteome Profiling
IgA nephropathy (IgAN) is a heterogeneous disease, which poses a series of challenges to accurate diagnosis and personalized therapy. Here, we present a systematic quantitative kidney tissue proteome atlas across 19 tumor-adjacent normal kidney tissues, 12 membranous nephropathy (MN) samples and 59 ...
ORGANISM(S): Homo Sapiens 
2022-03-22 | PXD032710 |
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