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TranscriptomicsSingle-cell transcriptional profiling of primary human dental follicle and derived organoids
Knowledge on tooth epithelial stem cells and corresponding biology in humans is sparse. Here, we developed an organoid model, typically replicating epithelial tissue stem cell biology, starting from human tooth. Dental follicle (DF), isolated from extracted wisdom teeth, efficiently generated long-t...
ORGANISM(S): Homo sapiens 
2022-04-01 | E-MTAB-10596 | biostudies-arrayexpress
ProteomicsPKC Inhibition by GÖ6976 Promotes Osteogenic Differentiation of Dental Follicle Cells via Activation of RhoA GTPase Signaling
Dental follicle cells (DFCs) are promising candidates for regenerative medicine due to their osteogenic potential. While the protein kinase C (PKC) inhibitor Gö6976 is known to enhance DFC differentiation, the underlying molecular mechanisms remain partially understood. Methods: We performed a pho...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD081715 | Pride
Dental follicle cells  osteogenesis  protein kinase c  rhogtpase  sost  phosphoproteomics 
TranscriptomicsExpression data from human dental follicle cells
We analysed the genexpression of dental follicle cells (DFCs) after 3 days osteogenic differentiation with BMP2 after transfection with a DLX3 plasmid (pDLX3) and after transfection with an empty plasmid (pEV) Total RNAs were isolated from dental follicle cells after transfection with pDLX3 and pEV ...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-59949 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of dental follicle cells after seven days of ostoeogenic differentiation
We analysed gene expression profiles in dental follicle cells after seven days of ostoeogenic differentiation Total RNAs were isolated from dental stem cells at day 0 (before differentiation) and after 7 days of differentiation)
ORGANISM(S): Homo sapiens 
2013-07-19 | E-GEOD-49007 | biostudies-arrayexpress
GenomicsSingle cell RNAseq analysis of PTHrP+ dental follicle cells
Single cell RNAseq analysis of PTHrP+ dental follicle cells
PRJNA491673 | ENA
TranscriptomicsGene expression profiles of dental follicle cells after 7 days of differentiation in vitro with BMP2, IGF2 and dexamethasone
We analysed gene expression profiles in dental follicle cells after 7 days of osteogenic differentiation with different inducers. Total RNAs were isolated from dental follicle cells after 7 days of differentiation with dexamethasone, BMP2, IGF2 and for control with standard cell culture medium
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-20963 | biostudies-arrayexpress
GenomicsPTHrP+ dental follicle cells
PTHrP+ dental follicle cells
PRJNA994951 | ENA
TranscriptomicsGene expression profiles of dental follicle cells after 48 hours of transfection in vitro with a DLX3 plasmid and an empty vector
We analysed gene expression profiles in dental follicle cells after 48 hours of overexpression with the transcription factor DLX3. Total RNAs were isolated from dental follicle cells after 48 hours of transfection with a DLX3 expressions plasmid and for control with an empty vector.
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-29753 | biostudies-arrayexpress
GenomicsComparative bulk RNAseq analysis of Control and Ptch1-deficient PTHrP+ dental follicle cells.
Comparative bulk RNAseq analysis of Control and Ptch1-deficient PTHrP+ dental follicle cells.
PRJNA994952 | ENA
GenomicsComparative bulk RNAseq analysis of Control and PTH/PTHrP recepter-deficient PTHrP+ dental follicle cells
Comparative bulk RNAseq analysis of Control and PTH/PTHrP recepter-deficient PTHrP+ dental follicle cells
PRJNA483765 | ENA
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