Dermal fibroblasts

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Unknown (2286)
Transcriptomics (1769)
Genomics (1044)
Proteomics (135)
Metabolomics (22)
Methylation profiling (21)
Other (17)
Models (2)
Genomic (1)

Organisms

Homo sapiens (1406)
Mus musculus (514)
Rattus norvegicus (23)
Bos taurus (18)
Sus scrofa (11)
Macaca mulatta (10)
Gallus gallus (8)
Toxoplasma gondii (5)
Rangifer tarandus (5)
Callithrix jacchus (4)
Macaca fascicularis (3)
Caenorhabditis elegans (3)
Pongo abelii (3)
Pan troglodytes (3)
Pan paniscus (3)
Equus caballus (2)
Oryctolagus cuniculus (2)
synthetic construct (2)
Eubalaena glacialis (1)
Human herpesvirus 5 strain Towne (1)
Rousettus aegyptiacus (1)
Ciona intestinalis (1)
Neospora caninum (1)
Ornithorhynchus anatinus (1)
Loxodonta africana (1)
Xenopus laevis (1)
mixed sample (1)
Cricetulus griseus (1)
Oncorhynchus mykiss (1)
Danio rerio (1)

Organisms

Homo sapiens (592)
Mus musculus (125)
Bos taurus (6)
Rattus norvegicus (5)
Rangifer tarandus (4)
Castor canadensis (3)
Pongo abelii (1)
Oryctolagus cuniculus (1)
Canis lupus familiaris (1)
Capra hircus (1)
Gallus gallus (1)
unidentified (1)

Repository

biostudies-arrayexpress (1373)
ENA (854)
geo (573)
pride (65)
EGA (49)
MassIVE (37)
jPOST (15)
MetaboLights (14)
iProX (11)
ExpressionAtlas (7)
GNPS (6)
GPMDB (3)
Cell Collective (2)
MetabolomicsWorkbench (2)
PanoramaPublic (2)
dbGaP (1)

Tissue

Fibroblast (44)
Cell culture (25)
Skin (24)
Skin fibroblast (3)
Fibroblast of dermis (3)
Stem cell (3)
Primary cell (3)
Fibroblast cells (2)
Keratinocyte (2)
Heart (2)
Amnion (1)
Regular cardiac myocyte (1)
Stromal cell (1)
Primary cell line cell (1)
Extracellular exosome (1)
Ciliary body (1)
Cornea (1)
Melanocyte (1)
Mesenchymal cell (1)
Dendritic cell (1)
Permanent cell line cell (1)
Blood cell (1)

Disease

Normal (11)
Wounds and Injuries (4)
Not Available (3)
Rheumatoid arthritis (2)
Adenocarcinoma (2)
Glioblastoma (2)
Breast cancer (2)
Systemic scleroderma (2)
Parkinson's disease (2)
Disease free (2)
Myelodysplasia (1)
Radiation-induced DNA damage (1)
Gastric carcinoma (1)
Mucopolysaccharidosis type 6 (1)
CUP (1)
Apert syndrome (1)
Mitochondrial complex I deficiency (1)
Hutchinson Gilford Progeria Syndrome (1)
Hutchinson-Gilford Progeria Syndrome (1)
AIDS-KS, HIV+, nodular (late) stage (1)
Epidermoid carcinoma (1)
Basal cell carcinoma, Gorlin-Goltz syndrome (1)
Alpha-1 antitrypsin deficiency (1)
Systemic sclerosis with diffuse scleroderma (1)
Short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome (1)
Control (1)
Peripheral primitive neuroectodermal tumor (1)
Pseudoxanthoma elasticum (1)
Dilated cardiomyopathy (1)
Atopic dermatitis (1)

Technology Type

Mass Spectrometry (67)
Shotgun proteomics (43)
Mass spectrometry (10)
Gel-based experiment (8)
Data-independent acquisition (4)
Bottom-up proteomics (4)
Illumina HiSeq 2000 (3)
SWATH MS (3)
Data-dependent acquisition (3)
Affinity purification coupled with mass spectrometry proteomics (3)
NMR spectroscopy (2)
Mass spectrometry assay (2)
MALDI (2)
SRM/MRM (2)
Top-down proteomics (2)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)
DiaPASEF (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (44)
Illumina NovaSeq 6000 (37)
Illumina HiSeq 4000 (22)
NextSeq 500 (22)
Illumina HiSeq 2000 (15)
NextSeq 550 (7)
Illumina NovaSeq X (4)
NextSeq 2000 (4)
Illumina HiSeq 1500 (4)
Bio-Rad CFX96 Real-time System (3)
BD LSRFortessa (2)
Illumina BeadArray reader (2)
G2565AA DNA microarray scanner [Agilent] (2)
ScanArray Express HT (2)
Axon GenePix 4000B scanning hardware (2)
NA (2)
DNBSEQ-G400 (2)
NanoDrop 2000 spectrophotometer (1)
Qiagen RNEasy Mini ki (1)
BD FACSAriaIIu cell sorter (1)
Poly-T oligo-attached magnetic beads (1)
Nikon Eclipse Ti2 with brightfield and fluorescence capacity (TRITC) (1)
Leica Biosystems Cryostat (1)
Advanced Sequencing Facility (1)
Epidermal cells : Trypsin dissociation / Dermal cells :MACS Whole Skin Dissociation Kit (1)
CL2 lab (1)
Punch biopsy - fibroblasts; commercial stock - HEKa (1)
MACS Whole Skin Dissociation Kit (1)
10x Chromium (1)
GeneChip Fluidics Station 450, GeneChip Scanner 3000 (1)

Publication Date

2013 (205)
2010 (178)
2014 (171)
2011 (151)
2015 (145)
2012 (138)
2016 (125)
2025 (95)
2024 (91)
2023 (90)
2022 (80)
2026 (78)
2018 (73)
2009 (73)
2008 (72)
2021 (67)
2019 (59)
2017 (55)
2020 (54)
2007 (41)
2006 (24)
2005 (24)
2004 (7)
2003 (1)

CHEBI ID

CHEBI:15891 (6)
CHEBI:18012 (6)
CHEBI:16027 (6)
CHEBI:17596 (6)
CHEBI:16856 (5)
CHEBI:16797 (5)
CHEBI:17268 (5)
CHEBI:37024 (5)
CHEBI:16865 (5)
CHEBI:16704 (5)
CHEBI:16737 (5)
CHEBI:16919 (5)
CHEBI:15354 (5)
CHEBI:16113 (4)
CHEBI:17553 (4)
CHEBI:44215 (4)
CHEBI:18132 (4)
CHEBI:25094 (4)
CHEBI:17202 (4)
CHEBI:18237 (4)
CHEBI:16695 (4)
CHEBI:17562 (4)
CHEBI:16870 (4)
CHEBI:16977 (4)
CHEBI:15428 (4)
CHEBI:16958 (4)
CHEBI:15741 (4)
CHEBI:6650 (4)
CHEBI:16335 (4)
CHEBI:17568 (4)

Metabolite Name

Creatinine (7)
L-Proline (6)
Taurine (5)
Creatine (5)
1-Methylnicotinamide (4)
IMP (4)
AMP (4)
L-Lysine (4)
Glutathione (4)
ADP (4)
L-Threonine (4)
Pantothenic acid (4)
Choline (4)
Adenosine (4)
Guanine (4)
L-Glutamine (4)
L-Serine (4)
Cytidine (4)
Xanthine (4)
Guanosine (4)
Uridine (4)
L-Valine (4)
L-Leucine (4)
Hypoxanthine (4)
D-Fructose (3)
L-Cystine (3)
L-Alanine (3)
Uracil (3)
Betaine (3)
Thiamine (3)

First Public Date

2014 (126)
2024 (106)
2025 (95)
2026 (73)
2022 (72)
2023 (70)
2018 (55)
2020 (52)
2021 (49)
2019 (47)
2017 (37)
2015 (32)
2016 (29)
2013 (11)

Modification

4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (863)
RNA-seq of coding RNA (151)
ChIP-seq (53)
RNA-seq of coding RNA from single cells (47)
Unknown experiment type (42)
Methylation profiling by array (37)
Comparative genomic hybridization by array (33)
Genotyping by array (20)
Other (17)
Methylation profiling by high throughput sequencing (15)
ChIP-chip by tiling array (10)
Transcription profiling by RT-PCR (10)
RNA-seq of non coding RNA (10)
RNA-seq of total RNA (7)
Transcription profiling by SAGE (5)
Cell line - High-throughput sequencing (5)
ATAC-seq (5)
Baseline (4)
Human - High-throughput sequencing (4)
Transcription profiling by tiling array (4)
ChIP-chip by array (4)
MicroRNA profiling by array (4)
High-throughput sequencing (2)
Human - One-color microarray (2)
Animal - High-throughput sequencing (2)
Hi-C (2)
Cell line - Single-cell sequencing (1)
Cell line - Methylation microarray (1)
MNase-seq (1)
Differential (1)

Release Date

2022 (282)
2021 (261)
2025 (244)
2023 (238)
2013 (230)
2014 (226)
2024 (223)
2010 (205)
2020 (201)
2015 (201)
2019 (189)
2011 (175)
2016 (168)
2012 (166)
2018 (164)
2017 (148)
2009 (81)
2008 (78)
2026 (59)
2007 (43)
2005 (30)
2006 (26)
2004 (12)
2001 (3)
1999 (3)
2003 (1)
2002 (1)
2000 (1)

Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (11)
Department of Molecular Biology and Genetics, Aarhus University, Denmark (2)
Department of Biomedical Science and Technology, Kyung Hee Medical Science Research Institute, Kyung Hee University, Seoul, South Korea (1)
Department of Biosciences, Durham University, UK (1)
Saint Louis University (1)
Head of the Necker Proteomics Plataform Paris France (1)
Univ Rennes, CNRS, Inserm, Biosit UAR 3480 US_S 018, Protim Core Facility, F-35000 Rennes, France (1)
Department Of Pharmacy (1)
Dept. of Immunobiology, University of Lausanne, Switzerland (1)
Department of Wound Infection and Drug, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing 400042, P. R. China (1)
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France; University of Paris, Imagine Institute, Paris, France; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA; Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France; Howard Hughes Medical Institute, New York, NY, USA (1)
Translational Matrix Biology, University of Cologne, Medical Faculty, Cologne Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases (CECAD)and Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany (1)
Corneal Stem Cell and Tissue Engineering Laboratory, Department of Ophthalmology and Visual Science, University of Illinois at Chicago (1)
IRCCS Istituto Ortopedico Galeazzi, Laboratorio di Applicazioni Biotecnologiche, Milan, Italy Department of Biomedical, Surgical and DentalSciences, Università degli Studi di Milano, Milan, Italy (1)
Proteomic Hematology Department of Experimental Medical Science Lund Stem Cell Center, Lund University (1)
Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Russia (1)
Functional Proteomics Laboratory Department of Science and Technology Federal University of São Paulo (ICT-UNIFESP) São José dos Campos, São Paulo, Brazil Rua Talim, 330, 12231-280; Tel +55 11 3385-4135 ext. 9727. (1)
Department of Biologyy, University of Rochester, NY, USA University of Rochester Mass Spectrometry Resource Laboratory, NY, USA (1)
Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China; Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, China. (1)
C3M – Inserm U1065 Centre Méditerranéen de Médecine Moléculaire Team: Microenvironment, signaling and cancer Bâtiment Universitaire ARCHIMED 151 route Saint Antoine de Ginestière BP 2 3194 06204 NICE CEDEX 3 (1)
Division of Cell Matrix Biology & Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK (1)
ETH Zurich, Institute of Molecular Health Sciences, Zurich, Switzerland (1)
Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (1)
UMB (1)
Univ. Lille, CNRS, USR 3290 - MSAP - Miniaturisation pour la Synthèse, l'Analyse et la Protéomique, F-59000 Lille, France (1)
ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. Da República, 2780-157 Oeiras, Portugal;iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901, Oeiras , Portugal (1)
Institute of Molecular and Cell Biology, University of Tartu, Riia 23b, 51010, Tartu, Estonia (1)
Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK (1)
Univ. Lille, U1286 – INFINITE – Institute for Translational Research in Inflammation, F59000 Lille, France (1)
Charité – Universitätsmedizin Berlin, Institute of Medical Genetics and Human Genetics, 13353 Berlin, Germany. (1)

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Eicosanoid profiles of dermal fibroblasts (part-II)

Not available

ORGANISM(S): Mus musculus

ST001254 | MetabolomicsWorkbench

Eicosanoid profiles of dermal fibroblasts (part-I)

Not available

ORGANISM(S): Mus musculus

ST001252 | MetabolomicsWorkbench

Selective galactose culture condition reveals distinct metabolic signatures in pyruvate dehydrogenase and complex I deficient human skin fibroblasts

INTRODUCTION: A decline in mitochondrial function represents a key factor of a large number of inborn errors of metabolism, which lead to an extremely heterogeneous group of disorders.

OBJECTIVES: To gain insight into the biochemical consequences of mitocho...

2021-10-06 | MTBLS761 | MetaboLights

Methylation Pattern of Human Dermal Fibroblasts

In this study, we have analyzed DNA methylation changes upon aging of human dermal fibroblasts by using the HumanMethylation27 BeadChip assessing 27,578 unique CpG sites. Cells were isolated from skin samples donated by young (6-23 years) and elderly (60-73 years) patients undergoing surgical interv...

ORGANISM(S): Homo sapiens

2012-02-14 | E-GEOD-22595 | biostudies-arrayexpress

scRNAseq of aging dermal fibroblasts

PRJNA435994 | ENA

CG methylated microarrays identify novel methylated sequence bound by the CEBPB|ATF4 heterodimer that are active in vivo

To evaluate the effect of CG methylation on DNA binding of sequence-specific B-ZIP transcription factors (TFs) in a high-throughput manner, we enzymatically methylated the cytosine in the CG dinucleotide on protein binding microarrays. Using this novel technology, we show that CG methylation enhanc...

ORGANISM(S): Mus musculus

2013-03-08 | E-GEOD-44942 | biostudies-arrayexpress

Transcription profiling of human fibroblasts from the stroma of squamous cell carcinoma and normal dermal fibroblasts

Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes. Epithelial-mesenchymal interaction between stromal fibroblasts and cancer cells influences the functional properties of tumor epithelium including the tumor progression and s...

ORGANISM(S): Homo sapiens

2009-12-31 | E-MTAB-97 | biostudies-arrayexpress

Transcription profiling of mouse dermal fibroblasts following exposure to endothelin-1

To determine if aberrant activation of endothelin-1 (Et1) could lead to the dysregulation of many downstream genes, we exposed fibroblasts to exogenous ET1 peptide and assayed for transcriptional changes by microarray. Mouse dermal fibroblasts were treated with exogenous Et1 peptide for 24 hours. ...

ORGANISM(S): Mus musculus

2007-06-29 | E-GEOD-4695 | biostudies-arrayexpress

Transcription profiling of mouse primary dermal fibroblasts treated with endothelin-1

Mouse primary dermal fibroblasts were treated with 100 nM endothelin-1 (ET1) synthetic peptide for 24 hours. Control samples received no ET1 peptide. The experiment compared treated to untreated to identify gene expression changes due to ET1 exposure. There are three biological replicates for bot...

ORGANISM(S): Mus musculus

2005-01-01 | E-MEXP-700 | biostudies-arrayexpress

Global gene expression analysis of human dermal fibroblasts treated with Wnt 3a compared to control cells

human dermal fibroblasts were treated with 100 ng/ml recombinant mouse Wnt 3a for 8 h and 24 h and compared to untreated controls at 8 and 24 h. RNA was isolated and microarray analysis was performed with Illumina Human Sentrix-6 BeadChip arrays

ORGANISM(S): Homo sapiens

2014-11-26 | E-MTAB-837 | biostudies-arrayexpress

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