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Transcriptomicsdermatomyositis
muscle biopsies of normal and dermatomyositis patients
ORGANISM(S): Homo sapiens 
2007-08-03 | E-GEOD-1551 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of CD19+ B-cell populations from patients with juvenile dermatomyositis and controls
RNA sequencing was used to compare the transcriptional state of ex-vivo B-cells from children with Juvenile dermatomyositis (JDM) pre- and on-treatment and age-matched healthy controls. RNA was extracted from blood samples that were taken from juvenile dermatomyositis patients at diagnosis (before t...
ORGANISM(S): Homo sapiens 
2019-01-03 | E-MTAB-5616 | biostudies-arrayexpress
TranscriptomicsFiorentino 2006-7 dermatomyositis, lupus, control skin
Background: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. Methodology and Findings: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....
ORGANISM(S): Homo sapiens 
2012-01-12 | E-GEOD-32245 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of skin biopsies from dermatomyositis patients and healthy controls
The purpose of this study was to use global gene expression analysis to determine major functional pathways and genes dysregulated in the skin of active rashes of dermatomyositis patients. These data will be used to help assign a diagnosis to skin biopsies from patients with rashes that are not cle...
ORGANISM(S): Homo sapiens 
2013-04-20 | E-GEOD-46239 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human muscles from untreated children with juvenile dermatomyositis
Background :To evaluate the impact of the duration of chronic inflammation on gene expression in skeletal muscle biopsies (MBx) from untreated children with juvenile dermatomyositis (JDM) and identify genes and biological processes associated with the disease progression, expression profiling data f...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-11971 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of muscle biopsies from patients with dermatomyositis or with polymyositis
Muscle biopsies were taken from 6 patients with dermatomyositis, 4 with polymyositis and 5 not myopathic subjects as controls. The genome-wide expression patterns were compared using Affymetrix HG-U133A chips. Experiment Overall Design: Gene expression profiles were generated for 15 individuals.
ORGANISM(S): Homo sapiens 
2011-04-23 | E-MEXP-2681 | biostudies-arrayexpress
GenomicsDermatomyositis skin transcriptomic signature
Dermatomyositis skin transcriptomic signature
PRJNA527138 | ENA
GenomicsTranscriptomic profiling of dermatomyositis lesions.
Transcriptomic profiling of dermatomyositis lesions.
PRJNA598373 | ENA
UnknownIdentification of Latent Diagnostic Biomarkers and Biological Pathways in Dermatomyositis Based on WGCNA.
Not available
S-EPMC8736700 | biostudies-literature
ProteomicsIn-depth data independent acquisition-mass spectrometry proteomic analysis of juvenile dermatomyositis serum samples reveals protein expression changes associated with muscle-specific autoantibodies
We analyzed sera from five JDM patients, each with three MSAs (anti-melanoma differentiation-associated protein 5 antibodies; anti-MDA5, anti-nuclear matrix protein 2 antibodies; anti-NXP2, or anti-transcriptional intermediary factor 1 alpha and/or gamma subunits antibodies; anti-TIF-1γ) and five he...
ORGANISM(S): Homo Sapiens (human) 
2023-04-23 | PXD036960 | JPOST Repository
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