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TranscriptomicsGene expression in the thymus medulla in the absence and presence of acute graft-versus-host disease
To investigate gene expression profile of medullary thymic epithelial cells with high surface density of MHC class II (mTEChigh), a murine parent into F1 hematopoietic stem cell transplantation model was administered. As recipient mice (B6xDBA/2)F1 (B6D2F1) were used that received either a syngeneic...
ORGANISM(S): Mus musculus 
2012-12-20 | E-MEXP-3745 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Acute GVHD is known to damage the structure of peripheral lymphoid organs. This study investigates how peripheral tolerance induction is affected by lymph node stroma damage in the context of graft-versus-host disease. Fibroblastic reticular cells (FRC) were flow sorted on day 7 post allo-BMT in mic...
ORGANISM(S): Mus musculus 
2020-01-14 | E-MTAB-8255 | biostudies-arrayexpress
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