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ProteomicsVCP–adaptor interactions are exceptionally dynamic and subject to differential modulation by a VCP inhibitor
In this study we use a combination of mass spectrometry-based proteomics and biophysical studies to characterize the interaction of adaptors with VCP. Our results reveal that most VCP–adaptor interactions are characterized by exceptionally rapid dynamics that in some cases are modulated by the VCP i...
ORGANISM(S): Homo sapiens (Human) 
2016-07-18 | PXD004105 | Pride
Ap-ms Sec-ms Vcp/p97 Protein complex dynamics Crosslinking-ms Orbitrap 
ProteomicsQuantitative Measurement of the Requirement of Diverse Protein Degradation Pathways in MHC Class I Peptide Presentation
The adaptive immune system distinguishes self from non-self by surveying peptides generated from degradation of intracellular proteins that are loaded onto MHC Class I molecules for display on the cell surface. While early studies reported that the bulk of cell surface MHC Class I complexes require ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-15 | MSV000091285 | MassIVE
UnknownThe Hydrogel Endovascular Aneurysm Treatment Trial (HEAT): A Randomized Controlled Trial of the Second-Generation Hydrogel Coil.
Not available
S-EPMC7534546 | biostudies-literature
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