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TranscriptomicsTranscriptome analysis of cryptococcal IPK mutants
In eukaryotes, inositol polyphosphates perform essential metabolic and signaling functions. Using human fungal pathogen Cryptococcus neoformans as a model, we created mutants in three inositol polyphosphates kinases: Arg1, Ipk1 and Kcs1. Each of the mutants produces a unique repertoire of inositol ...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2016-03-03 | E-GEOD-78824 | biostudies-arrayexpress
UnknownThe Crz1/Sp1 transcription factor of Cryptococcus neoformans is activated by calcineurin and regulates cell wall integrity.
Not available
S-EPMC3520850 | biostudies-literature
UnknownRapid microscopy and use of vital dyes: potential to determine viability of Cryptococcus neoformans in the clinical laboratory.
Not available
S-EPMC4308066 | biostudies-literature
UnknownInositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery.
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S-EPMC5753137 | biostudies-literature
UnknownIdentification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence.
Not available
S-EPMC4817067 | biostudies-literature
UnknownPhospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase.
Not available
S-EPMC3639591 | biostudies-literature
UnknownIP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote Cryptococcus neoformans infection in a mouse model.
Not available
S-EPMC5810508 | biostudies-literature
UnknownThe PHO signaling pathway directs lipid remodeling in Cryptococcus neoformans via DGTS synthase to recycle phosphate during phosphate deficiency.
Not available
S-EPMC6383925 | biostudies-literature
UnknownFungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity.
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S-EPMC4453010 | biostudies-literature
UnknownDesign, Synthesis, and Cellular Characterization of a New Class of IPMK Kinase Inhibitors.
Not available
S-EPMC12362615 | biostudies-literature
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