Sort   by:  
 Page size 
TranscriptomicsEpigenetic portraits of human breast cancers (methylation data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-20712 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (methylation data 2)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-22249 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (HCT116 cell line data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-20868 | biostudies-arrayexpress
TranscriptomicsGGI: a potential predictor of relapse for endocrine-treated breast cancer patients in the BIG 1-98 trial
Background: We have previously shown that the Gene expression Grade Index (GGI) was able to identify two subtypes of estrogen receptor (ER)-positive tumors that were associated with statistically distinct clinical outcomes in both untreated and tamoxifen-treated patients. Here, we aim to investigate...
ORGANISM(S): Homo sapiens 
2009-07-09 | E-GEOD-16391 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of human breast cancer during pregnancy
Using a dataset of 54 pregnant and 113 age/stage-matched non-pregnant breast cancer patients with complete clinical and survival data; we evaluated the pattern of hot spot somatic mutations and performed transcriptomic profiling using Sequenom® and Affymetrix®, respectively. Breast cancer molecular ...
ORGANISM(S): Homo sapiens 
2014-09-09 | E-GEOD-53031 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (various cell lines expression data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-22250 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (expression data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-20711 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancers to define clinically distinct molecular subtypes in estrogen receptor positive breast carcinomas using genomic grade
Purpose: A number of microarray studies have reported distinct molecular profiles of breast cancers (BC): basal-like, ErbB2-like and two to three luminal-like subtypes. These were associated with different clinical outcomes. However, although the basal and the ErbB2 subtypes are repeatedly recognize...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-6532 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (various cell lines methylation data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-22281 | biostudies-arrayexpress
GenomicsRNA Editing in breast cancer
High-throughput sequencing screens suggest that RNA editing, which consists in the substitution of adenosine with inosine by the RNA-specific adenosine deaminase (ADAR) enzyme, occurs at several thousand positions across the human genome. Recent evidences have shown that RNA-editing could promote pr...
EGAS00001000495 | EGA
Sort   by:  
 Page size