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TranscriptomicsDesmoglein 2 is a crucial receptor for adenovirus infection of epithelial cells
We have identified desmoglein 2 (DSG2) as the primary high-affinity receptor used by adenovirus (Ad) serotypes Ad3, Ad7, and Ad14. These serotypes represent important human pathogens causing respiratory tract infections. In epithelial cells, adenovirus binding to DSG2 triggers events reminiscent of ...
ORGANISM(S): Homo sapiens 
2010-12-08 | E-GEOD-24138 | biostudies-arrayexpress
ProteomicsEpidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling
Sorting transmembrane cargo is essential for tissue development and homeostasis. However, mechanisms of intracellular trafficking in stratified epidermis are poorly understood. Here we identify an interaction between the retromer endosomal trafficking component, VPS35, and the desmosomal cadherin, D...
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD036646 | Pride
Desmosome  keratinocyte  epidermal differentiation  skin disease  endosomal trafficking  retromer chaperone  vps35  sam syndrome  cadherin  dsg1  glut1  bioid 
GenomicsElectrophysiological defects in a novel patient-derived stem cell model of desmoglein-2 mutant ARVC
Electrophysiological defects in a novel patient-derived stem cell model of desmoglein-2 mutant ARVC
PRJNA735383 | ENA
UnknownAutoantibodies against desmoglein 2 are not pathogenic in pemphigus.
Not available
S-EPMC9073259 | biostudies-literature
UnknownDesmoglein isoform distribution affects stratum corneum structure and function.
Not available
S-EPMC2169464 | biostudies-literature
UnknownInvestigation of SNPs in the porcine desmoglein 1 gene.
Not available
S-EPMC1858681 | biostudies-literature
UnknownDesmoglein 2 mutant mice develop cardiac fibrosis and dilation.
Not available
S-EPMC3105238 | biostudies-literature
GenomicsMelanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration
Melanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration
PRJNA1000459 | ENA
UnknownDesmoglein-1, differentiation, and disease.
Not available
S-EPMC3613937 | biostudies-literature
TranscriptomicsElectrophysiological defects in a novel patient-derived stem cell model of desmoglein-2 mutant ARVC
Here we developed a novel human induced pluripotent stem cell (hiPSC) model of ARVC to gain insight into the electrical and biomolecular effects of desmoglein-2 (DSG2) mutation in cardiomyocytes. hiPSC-derived cardiomyocytes (hiPSC-CMs) were generated from peripheral blood mononuclear cells donated ...
ORGANISM(S): Homo sapiens 
2021-06-06 | GSE176209 | GEO
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