Sort   by:  
 Page size 
GenomicsDesmosomal protein degradation as underlying causes of arrhythmogenic cardiomyopathy
Desmosomal protein degradation as underlying causes of arrhythmogenic cardiomyopathy
PRJNA672884 | ENA
ProteomicsDesmosomal protein degradation accompanied by desmosomal and adherens junctions protein disarray as underlying causes of PKP2 driven arrhythmogenic cardiomyopathy
Arrhythmogenic cardiomyopathy (ACM) is an inherited progressive cardiomyopathy. The pathophysiological events are well understood, yet the underlying molecular mechanisms remain undefined. Here, we created a novel research platform comprising of patient originated hiPSC-derived cardiomyocytes bearin...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-18 | PXD020605 | Pride
Proteomics Pkp2 Desmosomal protein degradation Arrhythmogenic cardiomyopahty 
GenomicsDesmosomal protein degradation as underlying causes of arrhythmogenic cardiomyopathy [PKP2 c.1755delA/WT and WT]
Desmosomal protein degradation as underlying causes of arrhythmogenic cardiomyopathy [PKP2 c.1755delA/WT and WT]
PRJNA822100 | ENA
TranscriptomicsDesmosomal protein degradation as underlying causes of arrhythmogenic cardiomyopathy
Arrhythmogenic cardiomyopathy (ACM) is an inherited progressive cardiomyopathy. The pathophysiological events are well understood, yet the underlying molecular mechanisms remain undefined. Here we use patient originated hiPSC-derived cardiomyocytes bearing a pathogenic PKP2 mutation (PKP2 c.2013delC...
ORGANISM(S): Homo sapiens 
2023-03-23 | GSE160289 | GEO
TranscriptomicsDesmosomal protein degradation as underlying causes of arrhythmogenic cardiomyopathy [PKP2 c.1755delA/WT and WT]
Arrhythmogenic cardiomyopathy (ACM) is an inherited progressive cardiomyopathy. The pathophysiological events are well understood, yet the underlying molecular mechanisms remain undefined. Here we use patient originated hiPSC-derived cardiomyocytes bearing a pathogenic PKP2 mutation (PKP2 c.2013delC...
ORGANISM(S): Mus musculus 
2023-03-23 | GSE199925 | GEO
UnknownDesmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Not available
S-EPMC8159691 | biostudies-literature
UnknownYAP Inhibition by Verteporfin Causes Downregulation of Desmosomal Genes and Proteins Leading to the Disintegration of Intercellular Junctions.
Not available
S-EPMC9225343 | biostudies-literature
UnknownCleavage of Desmosomal Cadherins Promotes γ-Catenin Degradation and Benefits Wnt Signaling in Coxsackievirus B3-Induced Destruction of Cardiomyocytes.
Not available
S-EPMC7225294 | biostudies-literature
UnknownArmc8 is an evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions.
Not available
S-EPMC6680376 | biostudies-literature
UnknownDesmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner.
Not available
S-EPMC6581214 | biostudies-literature
Sort   by:  
 Page size