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TranscriptomicsGene expression profiles of C57BL/6 murine hepatocytes, murine embryonic stem cells (D3) and murine hepatocyte-reprogrammed induced Tissue Stem cells (iTSCs)
We have recently developed a new generation of induced stem cells that we have called “induced Tissue Stem cells” (iTSCs) which are generated by using low doses of non-integrative vectors encoding several embryonic reprogramming factors permitting to de-differentiate the cells without passing throug...
ORGANISM(S): Mus musculus 
2013-10-29 | E-GEOD-51782 | biostudies-arrayexpress
TranscriptomicsTranscriptome study of hepatocytes isolated from transgenic mice expressing HCV core.
Hepatitis C Virus (HCV) core protein plays a major role in HCV mediated liver pathologies. We have previously reported that HCV core variants isolated from tumoral (T) and non-tumoral (NT) livers were capable to alleviate Smad transcriptional activity and to shift TGF-β responses from tumor suppres...
ORGANISM(S): Mus musculus 
2012-03-03 | E-GEOD-36220 | biostudies-arrayexpress
TranscriptomicsExploring new pathways involved during experimental renal fibrogenesis in the Unilateral Ureteral Obstruction
Chronic kidney disease (CKD) is a burden for Public Health and concerns millions of individuals worldwide. Independently of the cause, CKD is secondary to the replacement of functional renal tissue by extra-cellular matrix proteins (i.e fibrosis) that progressively impairs kidney function. The patho...
ORGANISM(S): Mus musculus 
2013-02-10 | E-GEOD-38117 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of bone marrow mesenchymal stromal cells from patients with Primary Myelofibrosis
Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm whose severity and treatment complexity is attributed to the presence of bone marrow (BM) fibrosis and alterations of stroma impairing the production of normal blood cells. Despite the recently discovered mutations including the JA...
ORGANISM(S): Homo sapiens 
2015-01-10 | E-GEOD-44426 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of in vitro MSC-derived osteoblastic cells from patients with Primary Myelofibrosis
Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm whose severity and treatment complexity is attributed to the presence of bone marrow (BM) fibrosis and alterations of stroma impairing the production of normal blood cells. Despite the recently discovered mutations including the JA...
ORGANISM(S): Homo sapiens 
2015-01-10 | E-GEOD-46021 | biostudies-arrayexpress
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