Diacylglycerol lipase

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Unknown (202)
Transcriptomics (54)
Metabolomics (16)
Genomics (9)
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Organisms

Mus musculus (23)
Homo sapiens (9)
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Sinorhizobium fredii NGR234 (1)
Dinoroseobacter shibae DFL 12 = DSM 16493 (1)
Gordonia sp. KTR9 (1)
Rhodopseudomonas palustris (1)
Laccaria bicolor S238N-H82 (1)
Capra hircus (1)
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Candida albicans (1)
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Organisms

Mus musculus (4)
Homo sapiens (2)
Gordonia sp. KTR9 (1)

Repository

biostudies-arrayexpress (48)
MetaboLights (15)
pride (8)
ENA (8)
geo (6)
EVA (1)
GNPS (1)

Tissue

Cell culture (3)
Brain (2)
Kidney (2)
Cell suspension culture (1)
Fat cell (1)
Liver (1)
Macrophage (1)
Microglial cell (1)
Monocyte (1)
Placenta (1)
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Technology Type

Mass spectrometry assay (8)
Mass Spectrometry (8)
Mass spectrometry (7)
Data-dependent acquisition (3)
Bottom-up proteomics (2)
Shotgun proteomics (2)
Affinity purification coupled with mass spectrometry proteomics (1)
Data-independent acquisition (1)
HDMSE (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse-phase (4)
Liquid Chromatography MS - positive - reverse phase (4)
Gas Chromatography MS - positive (3)
Liquid Chromatography MS - positive - reverse-phase (3)
Liquid Chromatography MS - negative - reverse phase (3)
AB 3300 Genetic Analyzer (1)
LTQ-FT Thermo Scientific (1)
LTQ-FT (Thermo) (1)
Liquid Chromatography MS - alternating (1)
Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
LTQ-FT (1)
Liquid Chromatography MS - alternating - reverse phase (1)
Liquid Chromatography MS - negative - hilic (1)

Publication Date

2008 (11)
2010 (9)
2025 (9)
2014 (7)
2009 (5)
2018 (5)
2026 (5)
2021 (4)
2013 (4)
2015 (3)
2011 (3)
2023 (3)
2012 (2)
2007 (2)
2006 (2)
2024 (2)
2016 (1)
2004 (1)
2017 (1)

CHEBI ID

CHEBI:85691 (2)
CHEBI:86980 (2)
CHEBI:85701 (2)
CHEBI:85699 (2)
CHEBI:85698 (2)
CHEBI:85693 (2)
CHEBI:85692 (2)
CHEBI:86976 (2)
CHEBI:71731 (2)
CHEBI:85700 (2)
CHEBI:71728 (2)
CHEBI:71729 (2)
CHEBI:71730 (2)
CHEBI:71721 (2)
CHEBI:71722 (2)
CHEBI:66859 (2)
CHEBI:66856 (2)
CHEBI:64520 (2)
CHEBI:64423 (2)
CHEBI:64424 (2)
CHEBI:64561 (2)
CHEBI:64519 (2)
CHEBI:64525 (2)
CHEBI:64526 (2)
CHEBI:64446 (2)
CHEBI:64504 (2)
CHEBI:64523 (2)
CHEBI:64433 (2)
CHEBI:66857 (2)
CHEBI:64517 (2)

Metabolite Name

D-Fructose 6-phosphate (2)
Undecanedioic acid (2)
Maleic acid (2)
S-Adenosylmethionine (2)
L-Histidine (2)
Uracil (2)
3-Hydroxybutyric acid (2)
Malic acid (2)
L-Tryptophan (2)
Myristic acid (2)
Guanosine (2)
Uric acid (2)
Stearic acid (2)
L-Tyrosine (2)
Hippuric acid (2)
Hexadecanedioic acid (2)
4-Hydroxyphenylpyruvic acid (2)
Mevalonic acid (2)
4-Nitrophenol (2)
Azelaic acid (2)
Uridine (2)
UDP-N-acetylglucosamine (2)
Palmitic acid (2)
L-Glutamic acid (2)
DG 40:10 (IS) (1)
DG 40:8 (IS) (1)
DG 40:4 (IS) (1)
DG 40:0 (IS) (1)
DG 38:0 (IS) (1)
DG 34:0 (IS) (1)

First Public Date

2026 (1)
2024 (1)
2023 (1)
2021 (1)
2018 (1)
2017 (1)
2015 (1)
2014 (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (43)
RNA-seq of coding RNA (3)
Transcription profiling by SAGE (1)
Unknown experiment type (1)

Release Date

2022 (24)
2021 (20)
2015 (16)
2014 (16)
2020 (16)
2024 (15)
2016 (14)
2010 (14)
2018 (14)
2008 (13)
2023 (12)
2009 (10)
2025 (10)
2019 (10)
2012 (9)
2013 (8)
2011 (7)
2017 (7)
2026 (5)
2006 (3)
2004 (3)
2007 (2)
2001 (2)

Lab affiliation

Associate Professor Stephen F. and Fay Evans Martin Endowed Professorship in Chemistry CPRIT Scholar Department of Chemistry University of Texas at Austin (1)
Department of Chemistry, The Scripps Research Institute (1)
Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden, Netherlands. (1)
Department of Molecular Physiology, Leiden University & Oncode Institute, The Netherlands (1)
Department of Obstetrics and Gynecology, Medical University of Graz, Austria (1)
Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg, Germany. and German Center for Diabetes Research (DZD), Neuherberg, Germany;d German Center for Diabetes Research, Neuherberg, Germany (1)
Lundbeck La Jolla Research, San Diego, USA (1)
Molecular Physiology, Leiden Institute for Chemistry, Leiden University, The Netherlands (1)

Tags

xref:PubMed:37414748 (1)
xref:PubMed:34607960 (1)
xref:PubMed:29899429 (1)
xref:PubMed:24337578 (1)
xref:PubMed:38109529 (1)

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Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.

OBJECTIVE: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metabolic BAT activity.

2023-11-15 | MTBLS4082 | MetaboLights

Transcription profiling of mouse soleus muscle from hormone sensitive lipase-null animals

Expression analysis in order to elucidatethe role of hormone-sensitive lipase in soleus muscle.

ORGANISM(S): Mus musculus

2008-06-11 | E-GEOD-1772 | biostudies-arrayexpress

The ER-Associated Degradation Adapter Protein Sel1L Regulates Triglyceride Metabolism via Lipoprotein Lipase

Sel1L is an adaptor protein for the E3 ligase Hrd1 in the endoplasmic reticulum-associated degradation (ERAD), but its physiological role in a cell-type-specific manner remains unclear. Here we show that mice with adipocyte-specific Sel1L deficiency are resistant to diet-induced obesity and exhibit ...

ORGANISM(S): Mus musculus

2015-05-18 | E-GEOD-56918 | biostudies-arrayexpress

Liver gene expression profiling of lipoprotein lipase heterozygous knockout mice

Lipoprotein lipase (Lpl) was predicted as a causal gene for abdominal using a novel statistical method named LCMS (Schadt et al., 2005, Nature Genetics). In order to validate this prediction, we profiled the liver tissues of lipoprotein lipase heterozygous knockout mice (Lpl+/-) and their littermat...

ORGANISM(S): Mus musculus

2009-03-07 | E-GEOD-11991 | biostudies-arrayexpress

Assay and inhibition of diacylglycerol lipase activity.

Not available

S-EPMC3389199 | biostudies-literature

The effects of putative lipase and wax ester synthase/acyl-CoA:diacylglycerol acyltransferase gene knockouts on triacylglycerol accumulation and transcriptome expression in Gordonia sp. KTR9.

Gene disruption of KTR9_0186 resulted in a 2-fold increase in TAG content in nitrogen starved cells. Lipase mutants subjected to carbon starvation, following nitrogen starvation, retained 75% more TAGs and retained pigmentation. Transcriptome expression data confirmed the deletion of KTR9_0186 and i...

ORGANISM(S): Gordonia sp. KTR9

2015-02-14 | E-GEOD-60245 | biostudies-arrayexpress

Protein purification and cloning of diacylglycerol lipase from rat brain.

Not available

S-EPMC4892392 | biostudies-literature

The effect of diacylglycerol lipase alpha (DAGLA) on mRNA expression in hepatocellular carcinoma

PRJNA957783 | ENA

Fatty acid-releasing activities in Sinorhizobium meliloti include unusual diacylglycerol lipase.

Not available

S-EPMC4914366 | biostudies-literature

Transcription profiling of mouse liver samples comparing hormone sensitive lipase (HSL) knockout mice vs. wildtype

HSL is a key enzyme in in the mobilization of fatty acids from the triglyceride stores of white adipose tissue. In addition, it is expressed in mice liver. In the present microarray study, changes in the transcript profile of murine liver samples due to global HSL knockout were investigated. Experi...

ORGANISM(S): Mus musculus

2009-01-14 | E-GEOD-10067 | biostudies-arrayexpress

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289 Results

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