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MetabolomicsUrinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common kidney malignancy. Yet, no rapid, non-invasive biomarkers are available for diagnosis or screening. Urine represents an ideal analyte matrix due to its accessibility, low invasiveness, longitudinal sampling and the kidney’s central role i...

2026-08-16 | MTBLS12025 | MetaboLights
GenomicsMiR-146a-5p and miR-191-5p as novel diagnostic marker candidates for ovarian clear cell carcinoma
MiR-146a-5p and miR-191-5p as novel diagnostic marker candidates for ovarian clear cell carcinoma
PRJNA1000564 | ENA
ProteomicsThe identification of onchocerciasis biomarker candidates directly in human serum and urine
Onchocerca volvulus, the causative agent of onchocerciasis, infects over 20 million people and can cause severe dermatitis and ocular conditions including blindness. Current mass drug administration treatments do not kill female O. volvulus worms, and common diagnostic tests cannot reliably assess t...
ORGANISM(S): Homo Sapiens Onchocerca Volvulus 
2022-11-22 | PXD033659 |
ProteomicsProteomic profiling of serum extracellular vesicles identifies diagnostic markers for echinococcosis
In the present study, we employed a proteomics approach to identify parasite-derived proteins in the serum EVs from E. multilocularis-infected mice and assessed their diagnostic values. The study paves the way for the use of EVs to identify of diagnostic candidates and potentiates the applications o...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-11 | PXD036031 | Pride
Echinococcus multilocularis Extracellular vesicles 
GenomicsmiRNA profiling of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle
miRNA profiling of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle
PRJNA699634 | ENA
OtherMiR-146a-5p and miR-191-5p as novel diagnostic marker candidates for ovarian clear cell carcinoma
Ovarian cancer is a malignant gynecologic disease rarely diagnosed in the early stages. Among ovarian cancers, clear cell carcinoma has a poor prognosis due to its malignant potential. MicroRNAs (miRNAs) regulate gene expression in cells by suppressing the translation of the target gene or by degrad...
ORGANISM(S): Homo sapiens 
2023-10-06 | GSE239685 | GEO
ProteomicsNext-generation diagnostic biomarkers for vivax malaria
The global impact of Plasmodium vivax has been largely underestimated for several decades due to lower mortality rates compared to P. falciparum. However, in recent times, the parasite has become a serious threat to public health due to its ability to cause severe malaria with fatal outcomes. Its un...
ORGANISM(S): Plasmodium vivax 
2020-01-30 | PXD015165 | Pride
Multiple reaction monitoring Malaria Parasite Biomarker candidates Q exactive orbitrap Mass spectrometry Diagnosis 
GenomicsmiRNA profiling of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle
Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease that is a chronic wasting disease in ruminants. Spread of MAP is mainly provoked by a long subclinical stage during which MAP is shed into the environment with feces; accordingly, detection of subclinical animals is very import...
ORGANISM(S): Bos taurus 
2021-02-05 | GSE166230 | GEO
ProteomicsThoracic aortic diseases: Identification of diagnostic biomarkers using proteomic analysis
Introduction Thoracic aortic aneurysms frequently go undetected until serious complications like acute dissections or ruptures arise. Therefore, this study aims to identify potential blood circulating biomarkers enabling an easy and early diagnosis of thoracic aortic disease. Methods Potential bio...
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD061606 | Pride
Prm Proteomics Human plasma Exosomes 
ProteomicsIdentification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma - LC-MS Part
The aim of this study was the identification of biomarkers for the immunohistochemical diagnosis of cholangiocellular carcinoma (CCC). CCC is a primary cancer which arises from the epithelial cells of the bile ducts and is characterised by high mortality rates due to its late clinical presentation a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082885 | MassIVE
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