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TranscriptomicsTranscription profiling of human filaria induced monocyte dysfunction and its reversal following treatment
To assess the function of peripheral blood derived monocytes in patently infected filaria patients (either Wuchereria bancrofti, Mansonella perstans, or both), we investigated the cytokine production and gene expression profile of these cells in filaria infected patients and compared them with those...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2135 | biostudies-arrayexpress
TranscriptomicsThe expanded regulatory T cell population in chronic filarial infection is highly heterogeneous, activated and suppresses dendritic cell function indirectly through effector T cells.
Natural regulatory T cells (nTregs) are known to increase during chronic infection or at the site tumor, though the exact mechanisms that contribute to their accumulation and mode of action remain unclear. We used flow cytometry and microarray analyses to delineate the phenotype of nTregs and their ...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-44767 | biostudies-arrayexpress
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