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MetabolomicsGNPS - The nutritional and host environment shapes community ecology and keystone functions in a synthetic gut bacterial community
Microbe-microbe interactions are critical for gut microbiome function. A challenging task to understand health and disease-related microbiome signatures is to move beyond descriptive community-level profiling towards disentangling microbial interaction networks. Here, we aimed to determine members t...
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Sp. (ncbitaxon:10095) 
2022-11-14 | MSV000090704 | GNPS
TranscriptomicsEffect of live Mycobacterium leprae infection on global gene expression of primary human Schwann cells at 24 hours
In an attempt to understand M. leprae interaction with the human host, Stanford Genomics HEEBO Arrays were use to identify modulated genes in primary human Schwann cells infected with live M. leprae at a MOI of 100:1 for 24 hours. Dual channel competitive hybridizations between M. leprae infected an...
ORGANISM(S): Homo sapiens 
2013-01-03 | E-GEOD-40950 | biostudies-arrayexpress
TranscriptomicsCGH of common Candida albicans strains
The purpose of this review is to describe the tools used to detect genome changes, to highlight recent advances in our understanding of large scale chromosome changes that arise in C. albicans and to discuss the role of specific stresses in eliciting these genome changes. The types of genomic divers...
ORGANISM(S): Candida albicans 
2010-06-01 | E-GEOD-21643 | biostudies-arrayexpress
GenomicsNanopore sequencing on yeast expressing 4 murine DNMTs
Localisation of CpG methylation in yeast expressing murine DNMTS Genomic DNA was purified from a control strain and a strain expressing murine DNMTs
ORGANISM(S): Saccharomyces cerevisiae 
2020-09-30 | E-MTAB-9356 | biostudies-arrayexpress
TranscriptomicsGene expression profile from single cell level of retinal cells from optic cup of injected Abca4KO mice with miR-181a/b sponge therapeutic
We observed a beneficial effect on Abca4KO mice phenotype upon miR-181a/b sponge treatment. Then, we decided to perform single cell analysis to better understand the pathway associated with amelioration observed. Abca4KO mice were injected with miR-181a/b sponge in one eye and with a control vector ...
ORGANISM(S): Mus musculus 
2026-02-20 | E-MTAB-15988 | biostudies-arrayexpress
TranscriptomicsEffect of live Mycobacterium leprae on primary human Schwann cell gene expression
In attempt to understand M.leprae interaction with the human host, Applied Biosystems microarrays containing 30,865 probles were used to identify modulated genes in primary human Schwann Cells (SC) infected with live M. leprae at two early time points, 24 and 48 hours. A total of 4 independent exper...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-GEOD-35423 | biostudies-arrayexpress
Genomicsena-DATASET-Hospital Clinic Barcelona-21-07-2015-12:09:53:274-78 - samples
RNASeq sequencing. Each library was sequenced using TruSeq SBS Kit v3-HS, in paired-end mode with a read length of 2 × 76 bp. We generated more than 20 million paired-end reads for each sample in a fraction of a sequencing lane on HiSeq2000 (Illumina Inc.) following the manufacturer’s protoc...
EGAD00001001443 | EGA
TranscriptomicsSingle-cell transcriptomic profiling of 16 synovial sarcoma tumors
This study investigates the cellular heterogeneity of Synovial Sarcoma (SyS), an aggressive cancer defined by the SS18-SSX fusion oncogene and exhibiting diverse clinical behavior. We used single-cell RNA sequencing (scRNA-seq) on tumor samples from 16 patients to deconstruct this diversity at high ...
ORGANISM(S): Homo sapiens 
2025-10-16 | E-MTAB-15748 | biostudies-arrayexpress
TranscriptomicsCGH analysis of Candida albicans strains after in vitro evolution in the presence or absence of Fluconazole
Here we provide, for the first time, a longitudinal study of the prevalence, dynamics, and fixation of gross chromosomal rearrangements, including aneuploidy, in the presence and absence of fluconazole during a well-controlled in vitro evolution experiment. While no aneuploidy was detected in any o...
ORGANISM(S): Candida albicans 
2010-06-24 | E-GEOD-16423 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice Pax5 targets in B-macrophage bipotential lymphoma cells
B-macrophage bipotential lymphoma cells without Pax5 expression were reconstituted with the Pax5-estrogen receptor fusion protein and changes in transcription profiles in response to 4-hydroxytamoxifen were monitored in vivo
ORGANISM(S): Mus musculus 
2007-09-01 | E-MEXP-1156 | biostudies-arrayexpress
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